CASP7 Polyclonal Antibody
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CASP7 Polyclonal Antibody
| SKU # | E-AB-30758 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC-p |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC-p |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from the N-terminal region of human Caspase-7. |
| Abbre | CASP7 |
| Synonyms | Apoptotic protease MCH3, Apoptotic protease Mch-3, CASP-7, CASP7, CMH 1, CMH-1, CMH1, Caspase 7, Caspase 7 apoptosis related cysteine peptidase, Caspase-7 subunit p11, Caspase7, ICE LAP3, ICE-LAP3, ICE-like apoptotic protease 3, LICE2, MCH3 |
| Swissprot | |
| Calculated MW | 34 kDa |
| Observed MW | 35 kDa |
| Cellular Localization | Plasma Membrane |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
| IF | 1:200-1:1000 |
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Overexpression promotes programmed cell death.