Beta Tubulin Monoclonal Antibody
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Beta Tubulin Monoclonal Antibody
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| SKU # | E-AB-20093 |
| Reactivity | Human,  Mouse,  Rat |
| Host | Mouse |
| Applications | WB,  IF |
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Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human,  Mouse,  Rat |
| Applications | WB,  IF |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide |
| Abbre | β-tubulin |
| Synonyms | CDCBM,  CDCBM1,  CFEOM3,  CFEOM3A,  FEOM3,  M(beta)3,  M(beta)6,  MC1R,  Neuron specific beta III Tubulin,  Neuron-specific class III beta-tubulin,  QccE-11995,  QccE-15186,  TBB3,  TUBB3,  TUBB4,  Tubb 3,  Tubulin,  Tubulin beta 3,  Tubulin beta 3 chain,  Tubulin beta 4,  beta 3 tubulin,  beta-4 |
| Swissprot | |
| Calculated MW | 50 kDa |
| Observed MW | 55 kDa |
| Cellular Localization | Cytoplasm>cytoskeleton. |
| Tissue Specificity | Expression is primarily restricted to central and peripheral nervous system. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer,  Neuroscience,  Signal Transduction,  Tags and Cell Markers |
| Clone No. | 4A6 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:5000-10000 |
| IF | 1:100-200 |
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Background Â
TUBB3,the class III β tubulin or Tuj1,is selectively expressed in testis and neurons of the central and peripheral nervous system. It has been widely used as a marker for neurons. Aberrant expression of TUBB3 has also been found in various tumors of non-neural origin and can be used as a biomarker for cancer aggressiveness and a marker for the tendency to respond poorly to chemotherapy. This antibody is specific to TUBB3 but not cross-react with other tubulin isoforms.