BCL2 Monoclonal Antibody
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BCL2 Monoclonal Antibody
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| SKU # | E-AB-22004 |
| Reactivity | Human |
| Host | Mouse |
| Applications | WB |
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Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human |
| Applications | WB |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide |
| Abbre | Bcl-2 |
| Synonyms | 2,  AW986256,  Apoptosis regulator Bcl 2,  Apoptosis regulator Bcl-2,  Apoptosis regulator Bcl2,  B cell CLL/lymphoma 2,  B cell leukemia/lymphoma 2,  B-cell,  BCL2,  Bcl-2,  Bcl2,  C430015F12Rik,  D630044D05Rik,  D830018M01Rik,  Leukemia/lymphoma,  Oncogene B-cell leukemia 2,  PPP1R50 |
| Swissprot | |
| Calculated MW | 26 kDa |
| Observed MW | 26 kDa |
| Cellular Localization | Mitochondrion outer membrane. Nucleus membrane. Endoplasmic reticulum membrane. |
| Tissue Specificity | Expressed in a variety of tissues |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer,  Cell Biology,  Metabolism,  Signal Transduction |
| Clone No. | 1B3 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-2000 |
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Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).