TNF alpha Polyclonal Antibody Host Rabbit
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TNF alpha Polyclonal Antibody Host Rabbit
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| SKU # | E-AB-33121 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC-p, IF |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p, IF |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from the Internal region of human TNF-α |
| Abbre | TNF-α |
| Synonyms | APC1,  APC1 protein,  Cachectin,  DIF,  Differentiation inducing factor,  Macrophage cytotoxic factor,  TNF,  TNF superfamily,  TNF-a,  TNF-alpha,  TNFA,  TNFSF2,  Tnf,  Tumor n,  Tumor necrosis factor,  Tumor necrosis factor alpha,  macrophage derived,  member 2,  monocyte derived |
| Swissprot | |
| Calculated MW | 26 kDa |
| Observed MW | 16 kDa |
| Cellular Localization | Secreted and Cell membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer,  Cardiovascular,  Metabolism,  Immunology,  Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHCÂ | 1:100-1:300 |
| IF | 1:200-1:1000 |
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Background
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.