PPIB Monoclonal Antibody
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PPIB Monoclonal Antibody
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| SKU # | E-AB-22123 |
| Reactivity | Human,  Mouse,  Rat |
| Host | Mouse |
| Applications | WB,  IHC-p,  IF |
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Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human,  Mouse,  Rat |
| Applications | WB,  IHC-p,  IF |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide |
| Abbre | Cyclophilin B |
| Synonyms | AA408962,  AA553318,  AI844835,  CYP S1,  CYP-S1,  CYPB,  Cphn 2,  Cphn2,  CyP 20b,  Cyclophilin B,  Cyclophilin like protein,  EC 5.2.1.8,  MGC14109,  MGC2224,  OI9,  Peptidyl prolyl cis trans isomerase B precursor,  Peptidyl-prolyl cis-trans isome,  peptidyl prolyl cis trans isomerase B |
| Swissprot | |
| Observed MW | 21 kDa |
| Cellular Localization | Endoplasmic reticulum lumen. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer,  Immunology,  Signal Transduction |
| Clone No. | 4D7 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-2000 |
| IHC | 1:50-300 |
| IF | 1:50-300 |
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Background
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.