PDPK1 Polyclonal Antibody
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PDPK1 Polyclonal Antibody
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| SKU # | E-AB-32535 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC-p |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from human PDK1 around the non-phosphorylation site of Ser241. |
| Abbre | PDPK1 |
| Synonyms | 3 phosphoinositide dependent protein kinase 1,  3-phosphoinositide-dependent protein kinase 1,  MGC20087,  MGC35290,  OTTHUMP00000159109,  OTTHUMP00000159110,  OTTHUMP00000174525,  PDK1,  PDPK1,  PDPK2,  PDPK2P,  Pdpk1,  PkB kinase,  PkB kinase like gene 1,  PkB like 1,  hPDK 1,  hPDK1 |
| Swissprot | |
| Calculated MW | 63 kDa |
| Observed MW | 60 kDa |
| Cellular Localization | Cytoplasm. Membrane. Membrane-associated after cell stimulation leading to its translocation. Tyrosine phosphorylation seems to occur only at the plasma membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer,  Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
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Background
PDPK1 (3-phosphoinositide-dependent protein kinase 1) is a protein-coding gene. According to Gene Ontology (GO) annotations, this gene is associated with protein serine/threonine kinase activity and insulin receptor binding, indicating its role in signaling pathways related to cell growth, metabolism, and survival.