ERK 1 Monoclonal Antibody
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ERK 1 Monoclonal Antibody
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| SKU # | E-AB-22245 |
| Reactivity | Human,  Mouse,  Rat |
| Host | Mouse |
| Applications | IHC-p |
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Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human,  Mouse,  Rat |
| Applications | IHC-p |
| Clonality | Monoclonal |
| Immunogen | Recombinant Protein of ERK1 of MAPK3 |
| Abbre | ERK1 Mouse (5E9) |
| Synonyms | ERK,  ERK 1,  ERK-1,  ERK1,  ERT 2,  ERT2,  Extracellular Signal Regulated Kinase 1,  Extracellular signal related kinase 1,  Extracellular signal-regulated kinase 1,  HGNC6877,  HS44KDAP,  HUMKER1A,  Insulin Stimulated MAP2 Kinase,  Insulin-stimulated MAP2 kinase,  MAP,  MAP kinase 1 |
| Swissprot | |
| Cellular Localization | Cytoskeleton, Cytosol, Endosome, early endosome, late endosome, Extracellular region or secreted, extracellular exosome, Golgi apparatus, Golgi apparatus, Mitochondrion, Nucleus, nuclear envelope, nucleoplasm, nucleus, Plasma Membrane, caveola, plasma membrane, Other locations: cytoplasm, focal adhesion, protein complex, pseudopodium. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer,  Neuroscience,  Signal Transduction,  Stem Cells |
| Clone No. | 5E9 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:100-200 |
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Background
Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4).