Desmin Polyclonal Antibody Host Rabbit
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Desmin Polyclonal Antibody Host Rabbit
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| SKU # | E-AB-31185 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC-p, IF |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p, IF |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from the C-terminal region of human Desmin |
| Abbre | Desmin |
| Synonyms | CMD1I,  CSM1,  CSM2,  DES,  DESM,  Desmin,  FLJ12025,  FLJ39719,  FLJ41013,  FLJ41793,  Intermediate filament protein,  OTTHUMP00000064865 |
| Swissprot | |
| Calculated MW | 54 kDa |
| Observed MW | 55 kDa |
| Cellular Localization | Cytoplasm |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer,  Cardiovascular,  Signal Transduction,  Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
| IF | 1:200-1:1000 |
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Background
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.