CRKL Polyclonal Antibody
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CRKL Polyclonal Antibody
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| SKU # | E-AB-16360 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human,  Mouse,  Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CRKL |
| Abbre | CRKL |
| Synonyms | CRKL,  Crk L,  Crk like protein,  Crk-like protein,  Crkl,  Crkol,  HGNC:2363 ,  Oncogene CrkL,  V crk avian sarcoma virus CT10 oncogene homolog like,  V crk sarcoma virus CT10 oncogene homolog avian like,  v crk sarcoma virus CT10 oncogene homolog (avian) like |
| Swissprot | |
| Calculated MW | 34 kDa |
| Cellular Localization | Cytosol, Endosome, Extracellular region or secreted, extracellular exosome. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer,  Epigenetics and Nuclear Signaling,  Neuroscience,  Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
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Background
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.