CD327 Polyclonal Antibody
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CD327 Polyclonal Antibody
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| SKU # | E-AB-16314 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SIGLEC6 |
| Abbre | SIGLEC6 |
| Synonyms | CD327,  CD33 antigen-like 1,  CD33L,  CD33L1,  CD33L2,  CDw327,  OB-BP1,  OBBP1,  Obesity-binding protein 1,  SIGL6,  SIGLEC6,  Sialic acid-binding Ig-like lectin 6,  Siglec-6 |
| Swissprot | |
| Cellular Localization | Secreted and Cell membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
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Background
The SIGLEC6 gene to 19q13.3, which is where the CD33 gene is located.Putative adhesion molecule that mediates sialic-acid dependent binding to cells.Binds to alpha-2,6-linked sialic acid.The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine.