CD206 Polyclonal Antibody
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CD206 Polyclonal Antibody
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| SKU # | E-AB-33717 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC-p |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC-p |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from the Internal region of human CD206. |
| Abbre | CD206 |
| Synonyms | C type lectin domain family 13 member D,  C-type lectin domain family 13 member D,  CD 206,  CD206,  CD206 antigen,  CLEC13D,  CLEC13DL,  Macrophage mannose receptor,  Macrophage mannose receptor 1,  Macrophage mannose receptor 1 like protein 1,  Mannose receptor ,  bA541I19.1 |
| Swissprot | |
| Calculated MW | 166 kDa |
| Observed MW | 170 kDa |
| Cellular Localization | Membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer,  Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
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Background
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.