ANG2 Polyclonal Antibody
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ANG2 Polyclonal Antibody
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| SKU # | E-AB-40448 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
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Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human ANG2 protein expressed by E.coli |
| Abbre | ANGPT2 |
| Synonyms | ANG2,  ANGPT 2,  Agpt2,  Angiopoietin 2B,  Angiopoietin 2a,  Angiopoietin2,  Angpt2,  Tie2 ligand,  AGPT 2 |
| Swissprot | |
| Calculated MW | 57 kDa |
| Observed MW | 60-75 kDa |
| Cellular Localization | Secreted |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cardiovascular |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
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Related Reagents
| Applications | Recommended Dilution |
| WB | 1:250-1:500 |
| IHC | 1:50-1:200 |
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Background
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.