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MSE PRO Brettphos Pd G4, 98% Purity - MSE Supplies LLC

MSE PRO Brettphos Pd G4, 98% Purity

  • $ 30595
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MSE PRO™ Brettphos Pd G4, 98% Purity

MSE PRO™ Brettphos Pd G4 is an N-substituted 2-aminobiphenylpalladium methanesulfonate precatalyst. This precatalyst is valued for its versatility in promoting a wide range of cross-coupling reactions, including Suzuki-Miyaura, Heck, and Buchwald-Hartwig reactions. Its efficiency in mediating these transformations often leads to high yields of desired products while minimizing the formation of undesired by-products.

MSE Supplies offers various catalysts and ligands of coupling reaction. Please contact us for customization or bulk orders.

Technical Specifications:

CAS No. 1599466-83-7
Chemical name Brettphos Pd G4
Synonym(s)
  • BrettPhos Palladacycle Gen. 4
  • Methanesulfonato(2-dicyclohexylphosphino-3, 6-dimethoxy-2', 4', 6'-tri-i-propyl-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II)
Molecular formula C49H68NO5PPdS  
Pack size

1 g (CM1323)

5 g (CM1324)
Molecular weight 920.53 g/mol
Purity 98 %
Appearance Off-white to beige powder
Storage  Store at room temperature


References:

[1] Sotnik, S. A., Kolotilov, S. V., Radchenko, D. S., Ryabukhin, S. V., & Volochnyuk, D. M. (2019, August). G3 and G4 Buchwald precatalysts: Scale up, QC and application for the semi-automated parallel synthesis. In Proceedings of the ACS Fall National Meeting and Exposition, Abstracts of Papers of the American Chemical Society, San Diego, CA (pp. 25-29).

[2] Solazzo, M. (2022). High Throughput Experimentation in Pharmaceutical Process Chemistry (Doctoral dissertation, Johns Hopkins University).