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MSE PRO 7-Benzyl-1,7-diazaspiro[4.5]decane, ≥95.0% Purity - MSE Supplies LLC

MSE PRO 7-Benzyl-1,7-diazaspiro[4.5]decane, ≥95.0% Purity

SKU: CM1503

  • $ 67995
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MSE PRO™ 7-Benzyl-1,7-diazaspiro[4.5]decane, ≥95.0% Purity

MSE PRO™ 7-Benzyl-1,7-diazaspiro[4.5]decane features a distinctive spirocyclic pyrrolidine scaffold, which imparts structural rigidity and conformational constraints, making it an attractive building block for modulating biological targets. Spirocyclic pyrrolidines have garnered significant interest in medicinal chemistry due to their potential as therapeutic agents for various diseases, including obesity, diabetes, and neurological disorders. This compound presents an opportunity to explore its biological activity and develop novel derivatives.

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Technical Specifications:

CAS No. 1086395-20-1
Chemical name 7-Benzyl-1,7-diazaspiro[4.5]decane
Synonym(s)
  • 1,7-Diazaspiro[4.5]decane
  • 7-(phenylmethyl)-9-benzyl-1,9-diazaspiro[4.5]decane
Molecular formula C15H22N2  
Pack size

g (CM1503)

Molecular weight 230.35 g/mol
Purity ≥95.0%
Appearance White to gray solid 
Storage  Store at 2-8 °C


References:

[1] Smith, A. C., Cabral, S., Kung, D. W., Rose, C. R., Southers, J. A., García-Irizarry, C. N., ... & Griffith, D. A. (2016). The Synthesis of Methyl-Substituted Spirocyclic Piperidine-Azetidine (2, 7-Diazaspiro [3.5] nonane) and Spirocyclic Piperidine-Pyrrolidine (2, 8-Diazaspiro [4.5] decane) Ring Systems. The Journal of Organic Chemistry81(9), 3509-3519.

[2] Niu, A., Lin, L., Zhang, D., Jiang, K., Weng, D., Zhou, W., & Wang, J. (2022). Discovery of novel 2, 8-diazaspiro [4.5] decan-1-one derivatives as potent RIPK1 kinase inhibitors. Bioorganic & Medicinal Chemistry59, 116686.