{"product_id":"tjp1-polyclonal-antibody","title":"TJP1 Polyclonal Antibody","description":"\u003ch2\u003eTJP1 Polyclonal Antibody\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 69.7814px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd width=\"137\" style=\"height: 10px; width: 180.719px;\"\u003eSKU #\u003c\/td\u003e\n\u003ctd height=\"38\" class=\"xl65\" width=\"102\" style=\"height: 10px; width: 363.281px;\"\u003eE-AB-52081\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 19.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px; height: 19.5938px;\"\u003e\u003cspan\u003eHuman, Mouse, Rat\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 20.5938px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 20.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px; height: 20.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 180.719px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px; height: 19.5938px;\"\u003eIHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 130%; height: 423.063px;\" class=\"pro-table\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eHuman, Mouse, Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eIHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eSynthetic peptide of human TJP1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eTJP1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 70.375px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 70.375px;\" width=\"170\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 70.375px;\"\u003eTJP1,  Tight junction protein 1,  Tight junction protein ZO-1,  Tight junction protein ZO1,  ZO1,  Zo1,  Zona occludens 1,  Zona occludens 1 protein,  Zona occludens protein 1,  Zonula occludens 1 protein,  Zonula occludens protein 1,  zo-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003e\n\u003cdiv\u003e\u003ca href=\"https:\/\/www.uniprot.org\/uniprot\/Q07157\" title=\"Q07157\" class=\"text-primary mr-2\" target=\"_blank\"\u003eQ07157\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 39.1875px;\" width=\"170\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 39.1875px;\"\u003eCell membrane. Cell junction\u0026gt;tight junction. Movement of ZO-1 from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003e0.9 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eAntigen affinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eCancer,  Tags and Cell Markers\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 19.5938px;\" width=\"170\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 24.0997%; height: 39.1875px;\" width=\"170\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 39.1875px;\"\u003eThe product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 41.9688px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 22.375px;\"\u003e\n\u003ctd width=\"30%\" class=\"bold\" style=\"width: 39.6267%; height: 22.375px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd class=\"bold\" style=\"width: 60.0122%; height: 22.375px;\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 39.6267%; height: 19.5938px;\"\u003eIHC\u003c\/td\u003e\n\u003ctd style=\"width: 60.0122%; height: 19.5938px;\"\u003e1:30-1:150\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTight junction (or zonula occludens) form the continuous intercellular barrier between epithelial and endothelial cells,which is required to separate tissue spaces and regulate selective movement of solutes across the epithelium and endothelium . ZO-1 (also known as TJP1) is a peripheral membrane phosphoprotein located on the cytoplasmic face and is expressed in tight junctions of both epithelial and endothelial cells . It binds the transmembrane proteins occludin and the claudins linking them to cytoskeletal actin . ZO-1 belongs to a family of multidomain proteins known as the membrane-associated guanylate kinase homologs (MAGUKs). It is a pivotal tight junction protein and may be involved in signalling mechanisms regulating cell proliferation and differentiation.\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40889899352122,"sku":"E-AB-52081-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40889899384890,"sku":"E-AB-52081-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40889899417658,"sku":"E-AB-52081-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40889899450426,"sku":"E-AB-52081-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elabscience_613b415a-8af3-4f18-8bec-eb7822ed08d1.jpg?v=1748601222","url":"https:\/\/www.msesupplies.com\/products\/tjp1-polyclonal-antibody","provider":"MSE Supplies","version":"1.0","type":"link"}