{"product_id":"recombinant-human-kir2dl4-cd158d-protein-his-tag","title":"Recombinant Human KIR2DL4\/CD158D Protein (His Tag)","description":"\u003ch2\u003eRecombinant Human KIR2DL4\/CD158D Protein (His Tag)\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 29.5938px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd width=\"137\" style=\"width: 164.516px; height: 10px;\"\u003eSKU #\u003c\/td\u003e\n\u003ctd height=\"38\" class=\"xl65\" width=\"106\" style=\"height: 10px; width: 367.484px;\"\u003ePKSH032675\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 164.516px; height: 19.5938px;\"\u003eExpression Host\u003c\/td\u003e\n\u003ctd style=\"width: 367.484px; height: 19.5938px;\"\u003eHEK293 Cells\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003eDescription\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv id=\"dt_tab3\" class=\"dt01\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"dt01\"\u003e\n\u003cdiv class=\"dt01\" id=\"dt_tab1\"\u003e\n\u003ctable style=\"width: 104.745%; height: 293.907px;\" class=\"pro-table\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 97.9688px;\"\u003e\n\u003ctd style=\"width: 30.6338%; height: 97.9688px;\" width=\"170\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 69.0141%; height: 97.9688px;\"\u003eCD158 Antigen-Like Family Member D, CD158D, CD158d, G9P, KIR-103AS, KIR103AS, KIR2DL4, Killer Cell Immunoglobulin-Like Receptor 2DL4, Killer Cell Inhibitory Receptor 103AS, MHC Class I NK Cell Receptor KIR103AS\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 30.6338%; height: 19.5938px;\"\u003eSpecies\u003c\/td\u003e\n\u003ctd style=\"width: 69.0141%; height: 19.5938px;\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 30.6338%; height: 19.5938px;\" width=\"170\"\u003eExpression Host\u003c\/td\u003e\n\u003ctd style=\"width: 69.0141%; height: 19.5938px;\"\u003eHEK293 Cells\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 30.6338%; height: 19.5938px;\"\u003eSequence\u003c\/td\u003e\n\u003ctd style=\"width: 69.0141%; height: 19.5938px;\"\u003eTrp22-His242\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 30.6338%; height: 19.5938px;\"\u003eAccession\u003c\/td\u003e\n\u003ctd style=\"width: 69.0141%; height: 19.5938px;\"\u003eADY38409.1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 30.6338%; height: 39.1875px;\"\u003eCalculated Molecular Weight\u003c\/td\u003e\n\u003ctd style=\"width: 69.0141%; height: 39.1875px;\"\u003e25.3 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 30.6338%; height: 39.1875px;\"\u003eObserved Molecular Weight\u003c\/td\u003e\n\u003ctd style=\"width: 69.0141%; height: 39.1875px;\"\u003e30-40 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 30.6338%; height: 19.5938px;\"\u003eTag\u003c\/td\u003e\n\u003ctd style=\"width: 69.0141%; height: 19.5938px;\"\u003eC-His\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 30.6338%; height: 19.5938px;\"\u003eBio-activity\u003c\/td\u003e\n\u003ctd style=\"width: 69.0141%; height: 19.5938px;\"\u003eNot validated for activity\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n  \u003c\/div\u003e\n\u003cdiv class=\"dt01\" id=\"dt_tab1\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"dt01\" id=\"dt_tab1\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"dt01 detail_section\" id=\"dt_tab2\"\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"title\"\u003eProperties\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan class=\"title\"\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan class=\"title\"\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan class=\"title\"\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan class=\"title\"\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan class=\"title\"\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"dtl_table\" style=\"width: 100%; height: 297.469px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 17.1587%;\"\u003ePurity\u003c\/td\u003e\n\u003ctd style=\"width: 82.4723%;\"\u003e\u0026gt; 80 % as determined by reducing SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 17.1587%;\"\u003eEndotoxin\u003c\/td\u003e\n\u003ctd style=\"width: 82.4723%;\"\u003e\u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 78.375px;\"\u003e\n\u003ctd style=\"width: 17.1587%;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 82.4723%;\"\u003eGenerally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 17.1587%;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 82.4723%;\"\u003eThis product is provided as lyophilized powder which is shipped with ice packs.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 97.9688px;\"\u003e\n\u003ctd style=\"width: 17.1587%;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"width: 82.4723%;\"\u003eLyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.\u003cbr\u003eNormally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.\u003cbr\u003ePlease refer to the specific buffer information in the printed manual.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 42.75px;\"\u003e\n\u003ctd style=\"width: 17.1587%;\"\u003eReconstitution\u003c\/td\u003e\n\u003ctd style=\"width: 82.4723%;\"\u003ePlease refer to the printed manual for detailed information.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"dt01\" id=\"dt_tab3\"\u003e\n\u003cdiv id=\"dt_tab3\" class=\"dt01\"\u003e\n\u003cdiv class=\"dt01\"\u003e\n\u003cstrong\u003e\u003cspan class=\"title\"\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"dt01\"\u003e\n\u003cstrong\u003e\u003cspan class=\"title\"\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"dt01\"\u003e\n\u003cstrong\u003e\u003cspan class=\"title\"\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"dt01\"\u003e\u003cstrong\u003e\u003cspan class=\"title\"\u003e\u003cspan\u003eBackground\u003c\/span\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"dt01\"\u003e\n\u003cstrong\u003e\u003cspan class=\"title\"\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"dt01\"\u003eKiller cell immunoglobulin-like receptor 2DL4(KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"50μg","offer_id":40741489934394,"sku":"PKSH032675-50","price":309.95,"currency_code":"USD","in_stock":true},{"title":"10μg","offer_id":40741489967162,"sku":"PKSH032675-10","price":117.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/recombinant-human-kir2dl4-cd158d-protein-his-tag-50-g-elabscience-biotechnology-cell-assays-22531223945274.jpg?v=1752497854","url":"https:\/\/www.msesupplies.com\/products\/recombinant-human-kir2dl4-cd158d-protein-his-tag","provider":"MSE Supplies","version":"1.0","type":"link"}