{"product_id":"pms2-monoclonal-antibody-stored-at-2-8-c","title":"PMS2 Monoclonal Antibody Stored at 2~8°C","description":"\u003ch2\u003ePMS2 Monoclonal Antibody Stored at 2~8°C\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003e \u003c\/strong\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ctable class=\"pro-table\" style=\"width: 113.091%; height: 176.344px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 28.2468%;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 71.4286%;\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 28.2468%;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 71.4286%;\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 28.2468%;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 71.4286%;\"\u003eIHC-P\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 28.2468%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 71.4286%;\"\u003ePMS2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 28.2468%;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 71.4286%;\"\u003enucleus\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 28.2468%;\"\u003eTissue Specificity\u003c\/td\u003e\n\u003ctd style=\"width: 71.4286%;\"\u003eColon cancer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 28.2468%;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 71.4286%;\"\u003eThe RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 28.2468%;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 71.4286%;\"\u003eIce bag\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003e\u003cspan\u003eBackground\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003ePMS2 is a 96kDa mismatch repair protein that forms a heterodimer with MLH1 protein and is then activated in the presence of ATP. This complex coordinates the binding of other proteins that repair DNA errors that occur during cell division. Loss of PMS2 expression in tumor cells helped to identify hMLH1 mutation vectors and to determine whether they were suitable for mutational analysis. PMS2 defects are responsible for a small but significant proportion of colorectal cancers and a large proportion of tumors with microsatellite instability. PMS2 is associated with cases of the dominant genetic disease hereditary nonpolyposis colon cancer (HNPCC) and is commonly used in cancer studies together with MLH1, MSH2 and MSH6.\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"1.5ml","offer_id":40826856308794,"sku":"PA6729-1.5","price":177.95,"currency_code":"USD","in_stock":true},{"title":"3ml","offer_id":40826856341562,"sku":"PA6729-3","price":299.95,"currency_code":"USD","in_stock":true},{"title":"6mL","offer_id":40826856374330,"sku":"PA6729-6","price":548.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/pms2-monoclonal-antibody-stored-at-2-8-c-1-5ml-elabscience-biotechnology-biomarkers-22809384812602.jpg?v=1752499054","url":"https:\/\/www.msesupplies.com\/products\/pms2-monoclonal-antibody-stored-at-2-8-c","provider":"MSE Supplies","version":"1.0","type":"link"}