{"product_id":"ngef-polyclonal-antibody-reactivity-human","title":"NGEF Polyclonal Antibody Reactivity Human","description":"\u003ch2\u003eNGEF Polyclonal Antibody Reactivity Human\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable style=\"height: 73.7814px;\" width=\"503\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 10px;\"\u003e\u003cspan\u003eSKU #\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd height=\"38\" class=\"xl65\" width=\"102\" style=\"height: 10px; width: 363.281px;\"\u003eE-AB-52771\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 20.5938px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 20.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px; height: 20.5938px;\"\u003eHuman, \u003cspan\u003eMouse, Rat\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 23.5938px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 23.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px; height: 23.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 180.719px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px;\"\u003eWB, IHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pro-table\" style=\"width: 130%; height: 450.657px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eHuman, Mouse, Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eWB, IHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eFusion protein of human NGEF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eNGEF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 78.375px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eneuronal,  ARHGEF27,  EPHEXIN,  Eph receptor-interacting exchange protein,  Eph-interacting exchange protein,  Ephexin-1,  Guanine nucleotide exchange factor,  NGEF,  Neuronal guanine nucleotide exchange factor,  Ngef\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003e\n\u003cdiv\u003e\u003ca href=\"https:\/\/www.uniprot.org\/uniprot\/Q8N5V2\" title=\"Q8N5V2\" class=\"text-primary mr-2\" target=\"_blank\"\u003eQ8N5V2\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003e82 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eObserved MW\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eRefer to figures\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eCytoplasm. Membrane. Cell projection\u0026gt;growth cone. Associated with membranes. Localizes to axonal growth cones.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003e0.6 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eAntigen affinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eNeuroscience,  Signal transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24.0997%;\" width=\"170\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eThe product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 64.0313px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 23.125px;\"\u003e\n\u003ctd style=\"width: 35.8091%; height: 23.125px;\" class=\"bold\" width=\"30%\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 63.8299%; height: 23.125px;\" class=\"bold\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.3125px;\"\u003e\n\u003ctd style=\"width: 35.8091%; height: 21.3125px;\"\u003eWB \u003c\/td\u003e\n\u003ctd style=\"width: 63.8299%; height: 21.3125px;\"\u003e1:500-1:2000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 35.8091%; height: 19.5938px;\"\u003eIHC \u003c\/td\u003e\n\u003ctd style=\"width: 63.8299%; height: 19.5938px;\"\u003e1:30-1:150\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eActs as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40905193160762,"sku":"E-AB-52771-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40905193193530,"sku":"E-AB-52771-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40905193226298,"sku":"E-AB-52771-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40905193259066,"sku":"E-AB-52771-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elabscience_5fac5886-d524-4c1d-bf36-17d0c93f5ac5.jpg?v=1749817308","url":"https:\/\/www.msesupplies.com\/products\/ngef-polyclonal-antibody-reactivity-human","provider":"MSE Supplies","version":"1.0","type":"link"}