{"product_id":"wdr77-polyclonal-antibody-reactivity-human","title":"WDR77 Polyclonal Antibody Reactivity Human","description":"\u003ch2\u003eWDR77 Polyclonal Antibody Reactivity Human\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable style=\"height: 71.7814px;\" width=\"503\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 10px;\"\u003e\u003cspan\u003eSKU #\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 10px; width: 363.281px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-52236\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 20.5938px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 20.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px; height: 20.5938px;\"\u003eHuman, \u003cspan\u003eMouse\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.5938px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 21.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px; height: 21.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 180.719px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px;\"\u003eWB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pro-table\" style=\"width: 130%; height: 481.438px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eHuman, Mouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eWB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eFusion protein of human WDR77\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eWDR77\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 78.375px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 78.375px;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 78.375px;\"\u003e2610312E17Rik,  Androgen receptor cofactor p44,  C79984,  HKMT1069,  MEP 50,  MEP-50,  MEP50,  MGC2722,  Methylosome protein 50,  Nbla10071,  RGD1310479 ,  RP11 552M11.3,  WD,  WD repeat containing protein 77,  WD repeat domain 77 ,  WD repeat-containing protein 77,  p44,  p44\/Mep50\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"Q9BQA1\" href=\"https:\/\/www.uniprot.org\/uniprot\/Q9BQA1\" target=\"_blank\"\u003eQ9BQA1\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003e37 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eObserved MW\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eRefer to figures\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 58.7812px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 58.7812px;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 58.7812px;\"\u003eNucleus. Cytoplasm. Nuclear in Leydig cells and cytoplasmic in germ cells during fetal testicular development. In adult testis, predominantly nuclear. Subcellular location varies from nuclear to cytoplasmic in various tumors.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003e0.5 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eAntigen affinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 11.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 11.1875px;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 11.1875px;\"\u003eCancer,  Epigenetics and Nuclear Signaling,  Signal transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 19.5938px;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 19.5938px;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%; height: 39.1875px;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%; height: 39.1875px;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 33.0156px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"width: 39.6267%; height: 10px;\" class=\"bold\" width=\"30%\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 60.0122%; height: 10px;\" class=\"bold\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 23.0156px;\"\u003e\n\u003ctd style=\"width: 39.6267%; height: 23.0156px;\"\u003eWB\u003c\/td\u003e\n\u003ctd style=\"width: 60.0122%; height: 23.0156px;\"\u003e1:500-1:2000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40893760766010,"sku":"E-AB-52236-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40893760798778,"sku":"E-AB-52236-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40893760831546,"sku":"E-AB-52236-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40893760864314,"sku":"E-AB-52236-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elabscience_d5a19a29-f0bd-4893-822a-62b263c1150f.jpg?v=1748941811","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/wdr77-polyclonal-antibody-reactivity-human","provider":"MSE Supplies","version":"1.0","type":"link"}