{"product_id":"tribioscience-sphingosine-pkc-inhibitor-tbi2287","title":"Tribioscience Sphingosine, PKC Inhibitor (TBI2287)","description":"\u003ch2\u003eTribioscience Sphingosine, PKC Inhibitor (TBI2287)\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eResearch Use Only. Not intended for human use.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cspan data-text-len=\"63\" class=\"zw-portion zw-text-portion\"\u003eBuy Tribioscience products from MSE Supplies at the best value.\u003c\/span\u003e\u003cspan class=\"EOP-readonly EOP\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003cu\u003eProduct Details\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormal Name:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e(2S,3R,4E)-2-Amino-4-octadecene-1,3-diol\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAlternate Names:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eD(+)-erythro-1,3-Dihydroxy-2-amino-4-trans-octadecene\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eC\u003csub\u003e18\u003c\/sub\u003eH\u003csub\u003e37\u003c\/sub\u003eNO\u003csub\u003e2\u003c\/sub\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormula Weight:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e299.50\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCAS Number:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e123-78-4\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e\u0026gt;98%\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormulation:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003epowder\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eSoluble in DMSO (up to 25 mg\/ml with warming) or in Ethanol (up to 25 mg\/ml with warming).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e-20°C\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStability:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e≥ 1 year.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003cu\u003eApplications\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003ePKC inhibitor\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003cu\u003eFunctions\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eEndogenous sphingolipid found in cells esterified as phosphatidylcholine (sphingomyelin) and released by the action of sphingomyelinases. Potent and selective inhibitor of protein kinase C (IC50=1-3 µM). Inhibition is competitive with DAG, phorbol esters and Ca2+. May be phosphorylated by sphingosine kinases producing sphingosine-1-phosphate, a bioactive lipid producing a plethora of biological effects.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003cu\u003eApplication Procedures\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eFirst dissolved in DMSO (up to 25 mg\/ml with warming) or in Ethanol (up to 25 mg\/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 3 months.\u003c\/p\u003e","brand":"Tribioscience","offers":[{"title":"20 mg","offer_id":40966410108986,"sku":"TBI2287-20MG","price":118.95,"currency_code":"USD","in_stock":true},{"title":"100 mg","offer_id":40966410141754,"sku":"TBI2287-100MG","price":366.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/TBI2287.jpg?v=1754477740","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/tribioscience-sphingosine-pkc-inhibitor-tbi2287","provider":"MSE Supplies","version":"1.0","type":"link"}