{"product_id":"tribioscience-caspase-family-fluorometric-assay-kit-tbs2055","title":"Tribioscience Caspase-Family Fluorometric Assay Kit (TBS2055)","description":"\u003ch2 class=\"product_title entry-title show-product-nav\"\u003eTribioscience Caspase-Family Fluorometric Assay Kit (TBS2055)\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eResearch Use Only. Not intended for human use.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"vc_column_container col-md-8\"\u003e\n\u003cdiv class=\"wpb_wrapper vc_column-inner\"\u003e\n\u003cdiv class=\"wpb_text_column wpb_content_element\"\u003e\n\u003cdiv class=\"wpb_wrapper\"\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003e\u003cspan class=\"zw-portion zw-text-portion\" data-text-len=\"63\"\u003eBuy Tribioscience products from MSE Supplies at the best value.\u003c\/span\u003e\u003cspan class=\"EOP-readonly EOP\"\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan style=\"color: rgb(22, 22, 22);\"\u003e\u003cspan class=\"EOP-readonly EOP\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eApoptosis plays a fundamental role in many normal biological processes as well as in several disease states. Apoptosis can be induced by various stimuli that all produce the same end result: systematic and orderly cell death. The inflammasome is a large multiprotein complex whose assembly leads to the activation of caspase-1, which promotes the maturation of proinflammatory cytokines interleukin-1β (IL-1β) and IL-18. The Tribo™ CaspaseFamily fluorometric Assay Kits provide a simple and convenient means for assaying the activity of caspases family members (caspase-1, 2, 3, 4, 5, 6, 8, 9 \u0026amp;10). The assay is based on the detection of the free AFC fluorescence after cleavage from the labeled substrate. The free AFC can be quantified using a fluorometer or a fluorescence microtiter plate reader at Ex400\/Em505nm. Comparison of the fluorescence of AFC from an apoptotic sample with an uninduced control allows the determination of the fold increase in caspase-family member activity.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eStorage Conditions\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eStore Cell Lysis buffer and Assay buffer at 4℃, Store all other components at -20℃. Shelf life of six months.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Tribioscience","offers":[{"title":"9x25 Tests","offer_id":40941986250810,"sku":"TBS2055","price":571.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/TBS2055.jpg?v=1752469396","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/tribioscience-caspase-family-fluorometric-assay-kit-tbs2055","provider":"MSE Supplies","version":"1.0","type":"link"}