{"product_id":"tribioscience-caspase-3-fluorometric-assay-kit","title":"Tribioscience Caspase-3 Fluorometric Assay kit","description":"\u003ch2 class=\"product_title entry-title show-product-nav\"\u003eTribioscience Caspase-3 Fluorometric Assay kit\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eResearch Use Only. Not intended for human use.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"vc_column_container col-md-8\"\u003e\n\u003cdiv class=\"wpb_wrapper vc_column-inner\"\u003e\n\u003cdiv class=\"wpb_text_column wpb_content_element\"\u003e\n\u003cdiv class=\"wpb_wrapper\"\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003e\u003cspan class=\"zw-portion zw-text-portion\" data-text-len=\"63\"\u003eBuy Tribioscience products from MSE Supplies at the best value.\u003c\/span\u003e\u003cspan class=\"EOP-readonly EOP\"\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan style=\"color: rgb(22, 22, 22);\"\u003e\u003cspan class=\"EOP-readonly EOP\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"container\"\u003e\n\u003cdiv class=\"row main-content-wrap\"\u003e\n\u003cdiv class=\"main-content col-lg-12\"\u003e\n\u003cdiv id=\"primary\" class=\"content-area\"\u003e\u003cmain id=\"content\" class=\"site-main\"\u003e\n\u003cdiv id=\"product-4413\" class=\"product type-product post-4413 status-publish first instock product_cat-elisa has-post-thumbnail taxable shipping-taxable purchasable product-type-variable product-layout-sticky_info\"\u003e\n\u003cdiv class=\"woocommerce-tabs woocommerce-tabs-sxlv8mre resp-htabs\" id=\"product-tab\"\u003e\n\u003cdiv class=\"resp-tabs-container\"\u003e\n\u003cdiv class=\"tab-content resp-tab-content resp-tab-content-active\" id=\"tab-description\" aria-labelledby=\"tab_item-0\"\u003e\n\u003cdiv class=\"container\"\u003e\n\u003cdiv class=\"row main-content-wrap\"\u003e\n\u003cdiv class=\"main-content col-lg-12\"\u003e\n\u003cdiv id=\"primary\" class=\"content-area\"\u003e\u003cmain id=\"content\" class=\"site-main\"\u003e\n\u003cdiv id=\"product-8055\" class=\"product type-product post-8055 status-publish first instock product_cat-life-sciences product_cat-rt-pcr-kits has-post-thumbnail taxable shipping-taxable purchasable product-type-variable product-layout-default\"\u003e\n\u003cdiv class=\"woocommerce-tabs woocommerce-tabs-cw94o7ne resp-htabs\" id=\"product-tab\"\u003e\n\u003cdiv class=\"resp-tabs-container\"\u003e\n\u003cdiv class=\"tab-content resp-tab-content resp-tab-content-active\" id=\"tab-description\" aria-labelledby=\"tab_item-0\"\u003e\n\u003cdiv class=\"container\"\u003e\n\u003cdiv class=\"row main-content-wrap\"\u003e\n\u003cdiv class=\"main-content col-lg-12\"\u003e\n\u003cdiv class=\"content-area\" id=\"primary\"\u003e\u003cmain class=\"site-main\" id=\"content\"\u003e\n\u003cdiv class=\"product type-product post-9035 status-publish first instock product_cat-rt-pcr-kits has-post-thumbnail taxable shipping-taxable purchasable product-type-variable product-layout-default\" id=\"product-9035\"\u003e\n\u003cdiv id=\"product-tab\" class=\"woocommerce-tabs woocommerce-tabs-ctdv38rp resp-htabs\"\u003e\n\u003cdiv class=\"resp-tabs-container\"\u003e\n\u003cdiv aria-labelledby=\"tab_item-0\" id=\"tab-description\" class=\"tab-content resp-tab-content resp-tab-content-active\"\u003e\u003c\/div\u003e\n\u003cdiv aria-labelledby=\"tab_item-0\" class=\"tab-content resp-tab-content resp-tab-content-active\"\u003e\n\u003cp\u003eApoptosis plays a fundamental role in many normal biological processes as well as in several disease states. Apoptosis can be induced by various stimuli that all produce the same result: systematic and orderly cell death.\u003c\/p\u003e\n\u003cp\u003eCaspases cleave a variety of cellular substrates after aspartic acid residues – a characteristic that is central to their role in mammalian apoptosis. Caspases are synthesized in the cytosol of mammalian cells as inactive zymogens, which become active through intracellular caspase cascades.\u003c\/p\u003e\n\u003cp\u003eThe Tribio\u003csup\u003eTM\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eCaspase-3 fluorometric Assay Kits provide a simple and convenient method for the activity analysis of caspases that recognize the sequence DEVD. The assay is based on the detection of the free AFC fluorescence after cleavage from the labeled substrate DEVD-AFC. The free AFC can be quantified using a fluorometer or a fluorescence microtiter plate reader at Ex400\/Em505nm. Comparison of the fluorescence of AFC from an apoptotic sample with an uninduced control allows the determination of the fold increase in caspase-3 activity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eApoptosis\u003c\/li\u003e\n\u003cli\u003eDrug screening\u003c\/li\u003e\n\u003cli\u003eGrowth factors\u003c\/li\u003e\n\u003cli\u003eCytotoxicity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/main\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/main\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/main\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Tribioscience","offers":[{"title":"100 Tests","offer_id":40940334121018,"sku":"TBS2035","price":280.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/TBS2035.jpg?v=1752230841","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/tribioscience-caspase-3-fluorometric-assay-kit","provider":"MSE Supplies","version":"1.0","type":"link"}