{"product_id":"tribioscience-caspase-3-colorimetric-assay-kit-tbs2030","title":"Tribioscience Caspase-3 Colorimetric Assay Kit (TBS2030)","description":"\u003ch2 class=\"product_title entry-title show-product-nav\"\u003eTribioscience Caspase-3 Colorimetric Assay Kit (TBS2030)\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eResearch Use Only. Not intended for human use.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"vc_column_container col-md-8\"\u003e\n\u003cdiv class=\"wpb_wrapper vc_column-inner\"\u003e\n\u003cdiv class=\"wpb_text_column wpb_content_element\"\u003e\n\u003cdiv class=\"wpb_wrapper\"\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003e\u003cspan class=\"zw-portion zw-text-portion\" data-text-len=\"63\"\u003eBuy Tribioscience products from MSE Supplies at the best value.\u003c\/span\u003e\u003cspan class=\"EOP-readonly EOP\"\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan style=\"color: rgb(22, 22, 22);\"\u003e\u003cspan class=\"EOP-readonly EOP\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"container\"\u003e\n\u003cdiv class=\"row main-content-wrap\"\u003e\n\u003cdiv class=\"main-content col-lg-12\"\u003e\n\u003cdiv id=\"primary\" class=\"content-area\"\u003e\u003cmain id=\"content\" class=\"site-main\"\u003e\n\u003cdiv id=\"product-4413\" class=\"product type-product post-4413 status-publish first instock product_cat-elisa has-post-thumbnail taxable shipping-taxable purchasable product-type-variable product-layout-sticky_info\"\u003e\n\u003cdiv class=\"woocommerce-tabs woocommerce-tabs-sxlv8mre resp-htabs\" id=\"product-tab\"\u003e\n\u003cdiv class=\"resp-tabs-container\"\u003e\n\u003cdiv class=\"tab-content resp-tab-content resp-tab-content-active\" id=\"tab-description\" aria-labelledby=\"tab_item-0\"\u003e\n\u003cdiv class=\"container\"\u003e\n\u003cdiv class=\"row main-content-wrap\"\u003e\n\u003cdiv class=\"main-content col-lg-12\"\u003e\n\u003cdiv id=\"primary\" class=\"content-area\"\u003e\u003cmain id=\"content\" class=\"site-main\"\u003e\n\u003cdiv id=\"product-8055\" class=\"product type-product post-8055 status-publish first instock product_cat-life-sciences product_cat-rt-pcr-kits has-post-thumbnail taxable shipping-taxable purchasable product-type-variable product-layout-default\"\u003e\n\u003cdiv class=\"woocommerce-tabs woocommerce-tabs-cw94o7ne resp-htabs\" id=\"product-tab\"\u003e\n\u003cdiv class=\"resp-tabs-container\"\u003e\n\u003cdiv class=\"tab-content resp-tab-content resp-tab-content-active\" id=\"tab-description\" aria-labelledby=\"tab_item-0\"\u003e\n\u003cdiv class=\"container\"\u003e\n\u003cdiv class=\"row main-content-wrap\"\u003e\n\u003cdiv class=\"main-content col-lg-12\"\u003e\n\u003cdiv class=\"content-area\" id=\"primary\"\u003e\u003cmain class=\"site-main\" id=\"content\"\u003e\n\u003cdiv class=\"product type-product post-9035 status-publish first instock product_cat-rt-pcr-kits has-post-thumbnail taxable shipping-taxable purchasable product-type-variable product-layout-default\" id=\"product-9035\"\u003e\n\u003cdiv id=\"product-tab\" class=\"woocommerce-tabs woocommerce-tabs-ctdv38rp resp-htabs\"\u003e\n\u003cdiv class=\"resp-tabs-container\"\u003e\n\u003cdiv aria-labelledby=\"tab_item-0\" id=\"tab-description\" class=\"tab-content resp-tab-content resp-tab-content-active\"\u003e\u003c\/div\u003e\n\u003cdiv aria-labelledby=\"tab_item-0\" class=\"tab-content resp-tab-content resp-tab-content-active\"\u003e\n\u003cp\u003eApoptosis plays a fundamental role in many normal biological processes as well as in several disease states. Apoptosis can be induced by various stimuli that all produce the same end result: systematic and orderly cell death.\u003c\/p\u003e\n\u003cp\u003eCaspases cleave a variety of cellular substrates after aspartic acid residues—a characteristic that is central to their role in mammalian apoptosis. Caspases are synthesized in the cytosol of mammalian cells as inactive zymogens, which become active through intracellular caspase cascades.\u003c\/p\u003e\n\u003cp\u003eCaspase-3 Colorimetric Assay Kit provides a simple and convenient method for assaying the activity of caspase-3 that recognizes the sequence DEVD. The assay is based on spectrophotometric detection of the chromophore p-nitroaniline (pNA) after cleavage from the labeled substrate DEVD-pNA. The pNA light emission can be quantified using a spectrophotometer or a microtiter plate reader at 400- or 405-nm. Comparison of the absorbance of pNA from an apoptotic sample with an uninduced control allows determination of the fold increase in caspase-3 activity.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eApoptosis\u003c\/li\u003e\n\u003cli\u003eDrug screening\u003c\/li\u003e\n\u003cli\u003eGrowth factors\u003c\/li\u003e\n\u003cli\u003eCytotoxicity\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eStorage Conditions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eStore Cell Lysis buffer and Assay buffer at 4℃, Store all other components at -20℃. Shelf life of six months.\u003c\/span\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/main\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/main\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/main\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Tribioscience","offers":[{"title":"100 Tests","offer_id":40940312723514,"sku":"TBS2030","price":280.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/TBS2030.jpg?v=1752228725","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/tribioscience-caspase-3-colorimetric-assay-kit-tbs2030","provider":"MSE Supplies","version":"1.0","type":"link"}