{"product_id":"prkar2a-polyclonal-antibody","title":"PRKAR2A Polyclonal Antibody","description":"\u003ch2\u003ePRKAR2A Polyclonal Antibody\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 81.3752px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 19.5938px;\"\u003e\u003cspan\u003eSKU #\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; width: 363.281px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-52196\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 20.5938px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 20.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px; height: 20.5938px;\"\u003e\n\u003cspan\u003eHuman\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.5938px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 21.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px; height: 21.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 180.719px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px; height: 19.5938px;\"\u003e\u003cspan\u003eWB, IHC\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 130%; height: 411.063px;\" class=\"pro-table\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eWB, IHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eFusion protein of human PRKAR2A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003ePRKAR2A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 74.375px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003ecAMP dependent protein kinase regulatory subunit RII alpha,  cAMP dependent protein kinase regulatory subunit alpha 2,  cAMP dependent protein kinase type II alpha regulatory chain,  cAMP dependent protein kinase type II alpha regulatory subunit,  cAMP-dependent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"P13861\" href=\"https:\/\/www.uniprot.org\/uniprot\/P13861\" target=\"_blank\"\u003eP13861\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 23.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003e46 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eObserved MW\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eRefer to figures\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eCytoplasm. Cell membrane. Colocalizes with PJA2 in the cytoplasm and the cell membrane.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003e0.8 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eAntigen affinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eCancer,  Metabolism,  Signal Transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 62.3438px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 21.375px;\"\u003e\n\u003ctd width=\"30%\" class=\"bold\" style=\"width: 39.6267%; height: 21.375px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd class=\"bold\" style=\"width: 60.0122%; height: 21.375px;\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.375px;\"\u003e\n\u003ctd style=\"width: 39.6267%; height: 21.375px;\"\u003eWB \u003c\/td\u003e\n\u003ctd style=\"width: 60.0122%; height: 21.375px;\"\u003e1:500-1:2000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 39.6267%; height: 19.5938px;\"\u003eIHC\u003c\/td\u003e\n\u003ctd style=\"width: 60.0122%; height: 19.5938px;\"\u003e1:35-1:200\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ecAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40892483665978,"sku":"E-AB-52196-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40892483698746,"sku":"E-AB-52196-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40892483731514,"sku":"E-AB-52196-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40892483764282,"sku":"E-AB-52196-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elabscience_aa749107-1f57-401d-a376-8970a0d4c94b.jpg?v=1748863527","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/prkar2a-polyclonal-antibody","provider":"MSE Supplies","version":"1.0","type":"link"}