{"product_id":"phospho-cxcr4-ser339-polyclonal-antibody","title":"Phospho-CXCR4 (Ser339) Polyclonal Antibody","description":"\u003ch2\u003ePhospho-CXCR4 (Ser339) Polyclonal Antibody\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 78.7814px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20px;\"\u003e\n\u003ctd width=\"137\" style=\"height: 20px; width: 156.719px;\"\u003eSKU #\u003c\/td\u003e\n\u003ctd style=\"height: 20px; width: 387.281px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-21282\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 19.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003e\u003cspan\u003eHuman,  Mouse,  Rat,  Monkey\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 19.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003e\u003cspan\u003eRabbit\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 156.719px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003e\u003cspan\u003eWB,  IHC-p,  IF\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pro-table\" style=\"width: 99.8182%; height: 512.391px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eHuman,  Mouse,  Rat,  Monkey\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eWB,  IHC-p,  IF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eSynthesized peptide derived from human Fusin around the phosphorylation site of Ser339\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eC-X-C chemokine receptor type 4,  CD184,  CD184 antigen,  CXC-R4,  CXCR-4,  CXCR4,  Chemokine (C X C motif) receptor 4,  Chemokine CXC Motif Receptor 4,  D2S201E,  FB22,  Fusin,  HM89,  HSY3RR,  LAP 3,  LAP3,  LCR1,  LESTR,  Leuk,  Leukocyte derived seven transmembrane domain receptor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 34.5469px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"P61073\" href=\"https:\/\/www.uniprot.org\/uniprot\/P61073\" target=\"_blank\"\u003eP61073\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003e40 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eObserved MW\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003e38 kDa\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eCell membrane. In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eTissue Specificity\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eExpressed in numerous tissues, such as peripheral blood leukocytes, spleen, thymus, spinal cord, heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, cerebellum, cerebral cortex and medulla (in microglia as well as in astrocytes), brain microvascular, coronary artery and umbilical cord endothelial cells. Isoform 1 is predominant in all tissues tested.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003e1 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eCancer,  Metabolism,  Immunology,  Microbiology,  Neuroscience,  Stem Cells\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 18.6267%;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 81.0172%;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 42.7188px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 23.125px;\"\u003e\n\u003ctd width=\"30%\" class=\"bold\" style=\"width: 35.4596%; height: 23.125px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd class=\"bold\" style=\"width: 64.1793%; height: 23.125px;\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 35.4596%;\"\u003eWB\u003c\/td\u003e\n\u003ctd style=\"width: 64.1793%;\"\u003e1:500-1:2000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 35.4596%; height: 19.5938px;\"\u003eIHC\u003c\/td\u003e\n\u003ctd style=\"width: 64.1793%; height: 19.5938px;\"\u003e1:100-1:300\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 35.4596%;\"\u003eIF\u003c\/td\u003e\n\u003ctd style=\"width: 64.1793%;\"\u003e1:200-1:1000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e   \u003c\/p\u003e\n\u003cp\u003eThis gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1.The protein has 7 transmembrane regions and is located on the cell surface.It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells.Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome.Alternate transcriptional splice variants, encoding different isoforms, have been characterized.\u003cbr\u003e\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40884339146810,"sku":"E-AB-21282-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40884339179578,"sku":"E-AB-21282-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40884339212346,"sku":"E-AB-21282-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40884339245114,"sku":"E-AB-21282-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/E-AB-21282-1.jpg?v=1748340464","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/phospho-cxcr4-ser339-polyclonal-antibody","provider":"MSE Supplies","version":"1.0","type":"link"}