{"product_id":"orchid-scientific-diffusion-cell-apparatus-with-external-temperature-sensor","title":"Orchid Scientific Diffusion Cell Apparatus with External Temperature Sensor","description":"\u003ch2\u003eOrchid Scientific Diffusion Cell Apparatus with External Temperature Sensor\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eIN-VITRO SKIN PERMEATION STUDIES OF TOPICAL\u003c\/em\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e\u003cem\u003eFORMULATIONS\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe Vertical Franz Diffusion Cell is a simple, reproducible test for measuring the in vitro drug release from creams, ointments and gels. The Franz Cell consists of two primary chambers separated by a membrane. The test product is applied to the membrane via\u003cbr\u003ethe top chamber- donor compartment. The bottom chamber receptor compartment contains fluid from which samples are taken at regular intervals for analysis. This testing determines the amount of active drug that has permeated the membrane at each time point.\u003c\/p\u003e\n\u003ch3\u003eFeatures:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eVibration-free electromagnetic stirrer.\u003c\/li\u003e\n\u003cli\u003eExternal temperature sensor probe to determine temperature of media inside the cell (For Model JFDC07-O30)\u003c\/li\u003e\n\u003cli\u003eData logging for stirring speed and temperature at a sampling interval.\u003c\/li\u003e\n\u003cli\u003eMulti-language screen selection.\u003c\/li\u003e\n\u003cli\u003eTouch screen display with 20 in-built programs.\u003c\/li\u003e\n\u003cli\u003eThe same system can be upgraded to multi-station by adding one more stirrer unit.\u003c\/li\u003e\n\u003cli\u003eAudio\/visual alarms for sampling intervals.\u003c\/li\u003e\n\u003cli\u003eStirring on\/off option prior to sampling.\u003c\/li\u003e\n\u003cli\u003eHighly accurate stirring speeds and temperature.\u003c\/li\u003e\n\u003cli\u003eHeated circulating water bath with water level sensors to avoid damage to the heating element.\u003c\/li\u003e\n\u003cli\u003eDouble wall Heated circulating water bath ensuring more precise temperature control.\u003c\/li\u003e\n\u003cli\u003ePassword-protected data collection and report generation software with admin features.\u003c\/li\u003e\n\u003cli\u003eCalibration report generation facility in the software.\u003c\/li\u003e\n\u003cli\u003eGraphical presentation of data.\u003c\/li\u003e\n\u003cli\u003eProvision to add experiment title \u0026amp; comment.\u003c\/li\u003e\n\u003cli\u003eData can be converted to Excel \u0026amp; Pdf files for further analysis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eThe Transdermal Diffusion cell apparatus is remarkably simple to operate; the system \u003c\/strong\u003e\u003cstrong\u003eis supplied with:\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSix or seven-stage magnetic stirrer with cell holders.\u003c\/li\u003e\n\u003cli\u003eHeated circulating water bath with water level sensor.\u003c\/li\u003e\n\u003cli\u003eTouch screen control unit for control of speed and temperature.\u003c\/li\u003e\n\u003cli\u003eDiffusion Cells \u0026amp; accessories pack.\u003c\/li\u003e\n\u003cli\u003eJacked reservoir beaker for diffusion media.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/JFDC_06-_O30.jpg?v=1783528062\"\u003e\u003c\/p\u003e\n\u003ch3\u003eSpecifications:\u003c\/h3\u003e\n\u003ctable style=\"border-collapse: collapse; width: 383pt;\" width=\"511\" cellspacing=\"0\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ccolgroup\u003e \u003ccol style=\"mso-width-source: userset; mso-width-alt: 8331; width: 179pt;\" width=\"239\"\u003e \u003ccol style=\"mso-width-source: userset; mso-width-alt: 9495; width: 204pt;\" width=\"272\"\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 14.5pt;\" height=\"19\"\u003e\n\u003ctd style=\"height: 14.5pt; width: 179pt;\" width=\"239\" class=\"xl67\" height=\"19\"\u003eSpecification\u003c\/td\u003e\n\u003ctd style=\"width: 204pt;\" width=\"272\" class=\"xl67\"\u003eModel\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 58.0pt;\" height=\"77\"\u003e\n\u003ctd style=\"height: 58.0pt;\" height=\"77\"\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 204pt;\" width=\"272\" class=\"xl65\"\u003eJFDC 07- O30\u003cbr\u003e(Single Stirrer Unit)\u003cbr\u003eJFDC 07- O30 x 2\u003cbr\u003e(Dual Stirrer Unit)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 14.5pt;\" height=\"19\"\u003e\n\u003ctd style=\"height: 14.5pt;\" class=\"xl66\" height=\"19\" colspan=\"2\"\u003eStirrer Drive\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 58.0pt;\" height=\"77\"\u003e\n\u003ctd style=\"height: 58.0pt;\" height=\"77\"\u003eStirrer drive\u003c\/td\u003e\n\u003ctd style=\"width: 204pt;\" width=\"272\" class=\"xl65\"\u003e7 stage electromagnetic:\u003cbr\u003e01 (JFDC 07-O30)\u003cbr\u003e7 stage electromagnetic:\u003cbr\u003e02 (JFDC 07-O30 x 2)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 14.5pt;\" height=\"19\"\u003e\n\u003ctd style=\"height: 14.5pt;\" height=\"19\"\u003eMaterial of construction of enclosure\u003c\/td\u003e\n\u003ctd\u003eS.S. 304\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 14.5pt;\" height=\"19\"\u003e\n\u003ctd style=\"height: 14.5pt;\" height=\"19\"\u003eRPM Indicator\u003c\/td\u003e\n\u003ctd\u003eDigital (Touch Screen)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 14.5pt;\" height=\"19\"\u003e\n\u003ctd style=\"height: 14.5pt;\" height=\"19\"\u003eStirring Speed Range \u0026amp; Accuracy\u003c\/td\u003e\n\u003ctd\u003e200- 800 rpm (±1.0%)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 14.5pt;\" height=\"19\"\u003e\n\u003ctd style=\"height: 14.5pt;\" class=\"xl66\" height=\"19\" colspan=\"2\"\u003eHeated Circulating Water Bath (WCS02)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 14.5pt;\" height=\"19\"\u003e\n\u003ctd style=\"height: 14.5pt;\" height=\"19\"\u003eMaterial of construction of enclosure\u003c\/td\u003e\n\u003ctd\u003eDouble wall S.S. 304\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 29.0pt;\" height=\"39\"\u003e\n\u003ctd style=\"height: 29.0pt;\" height=\"39\"\u003eTemperature range and accuracy\u003c\/td\u003e\n\u003ctd style=\"width: 204pt;\" width=\"272\" class=\"xl65\"\u003e5°C Above ambient to\u003cbr\u003e60°C (±0.5 °C)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 14.5pt;\" height=\"19\"\u003e\n\u003ctd style=\"height: 14.5pt;\" height=\"19\"\u003eInter cell temperature variation\u003c\/td\u003e\n\u003ctd\u003e±1.0 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 14.5pt;\" height=\"19\"\u003e\n\u003ctd style=\"height: 14.5pt;\" height=\"19\"\u003eInter cell stirring speed variation\u003c\/td\u003e\n\u003ctd\u003e±1.0 %\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 14.5pt;\" height=\"19\"\u003e\n\u003ctd style=\"height: 14.5pt;\" height=\"19\"\u003eTemperature Indicator\u003c\/td\u003e\n\u003ctd\u003eDigital (Touch screen)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 14.5pt;\" height=\"19\"\u003e\n\u003ctd style=\"height: 14.5pt;\" height=\"19\"\u003eCertifications\u003c\/td\u003e\n\u003ctd\u003eCE Compliant\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 29.0pt;\" height=\"39\"\u003e\n\u003ctd style=\"height: 29.0pt;\" height=\"39\"\u003ePower requirements\u003c\/td\u003e\n\u003ctd style=\"width: 204pt;\" width=\"272\" class=\"xl65\"\u003e220\/230V AC 50Hz,\u003cbr\u003e110\/120V AC 50-60Hz*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 14.5pt;\" height=\"19\"\u003e\n\u003ctd style=\"height: 14.5pt;\" height=\"19\"\u003eExternal temperature sensor\u003c\/td\u003e\n\u003ctd\u003eYES\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003eOrdering Information:\u003c\/h3\u003e\n\u003cstyle\u003e\n.spec-table-wrapper{\n    overflow-x:auto;\n}\n\n.spec-table{\n    width:100%;\n    border-collapse:collapse;\n    font-family:Arial, Helvetica, sans-serif;\n    font-size:14px;\n    color:#222;\n    background:#ffffff;\n}\n\n.spec-table th,\n.spec-table td{\n    border:1px solid #d9d9d9;\n    padding:10px;\n    vertical-align:top;\n    text-align:left;\n    background:#ffffff;\n    line-height:1.5;\n}\n\n.spec-table th{\n    font-weight:700;\n}\n\n.spec-table ul{\n    margin:0;\n    padding-left:20px;\n}\n\u003c\/style\u003e\n\u003cdiv class=\"spec-table-wrapper\"\u003e\n\u003ctable style=\"border-collapse: collapse; width: 434pt;\" width=\"576\" cellspacing=\"0\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ccolgroup\u003e \u003ccol style=\"width: 63px;\" width=\"64\"\u003e \u003ccol style=\"width: 111px;\" width=\"110\"\u003e \u003ccol style=\"width: 93px;\" width=\"93\"\u003e \u003ccol style=\"width: 100px;\" width=\"100\"\u003e \u003ccol style=\"width: 119px;\" width=\"118\"\u003e \u003ccol style=\"width: 92px;\" width=\"91\"\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 42.0pt;\" height=\"56\"\u003e\n\u003ctd style=\"height: 42.0pt; width: 48pt;\" width=\"64\" class=\"xl65\" height=\"56\"\u003e\u003cstrong\u003eModel\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 83pt;\" width=\"110\" class=\"xl65\"\u003e\u003cstrong\u003eStirring drive\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 70pt;\" width=\"93\" class=\"xl66\"\u003e\n\u003cstrong\u003eHeated\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003ecirculating\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003ewater bath\u003c\/strong\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 75pt;\" width=\"100\" class=\"xl65\"\u003e\u003cstrong\u003eCells Supplied\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 89pt;\" width=\"118\" class=\"xl66\"\u003e\n\u003cstrong\u003eAccessories\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003esupplied\u003c\/strong\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 69pt;\" width=\"91\" class=\"xl65\"\u003e\u003cstrong\u003eOptional\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 350.0pt;\" height=\"467\"\u003e\n\u003ctd style=\"height: 350.0pt; width: 48pt;\" width=\"64\" class=\"xl67\" height=\"467\"\u003e\u003cspan\u003eJFDC\u003cbr\u003e07-O030\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 83pt;\" width=\"110\" class=\"xl67\"\u003e7 stage\u003cbr\u003eelectromagnetic\u003cbr\u003estirrer drive: 01\u003c\/td\u003e\n\u003ctd style=\"width: 70pt;\" width=\"93\" class=\"xl67\"\u003eDouble wall\u003cbr\u003eHeated\u003cbr\u003ecirculating\u003cbr\u003ewater bath: 01\u003cbr\u003eunit\u003c\/td\u003e\n\u003ctd style=\"width: 75pt;\" width=\"100\" class=\"xl67\"\u003e-Glass diffusion\u003cbr\u003ecell of 20ml\u003cbr\u003ecapacity with\u003cbr\u003e20mm\u003cbr\u003eexposure area:\u003cbr\u003e06Nos\u003cbr\u003e(20ml cells are\u003cbr\u003eby default. If\u003cbr\u003euser wants to\u003cbr\u003eselect any\u003cbr\u003eother capacity\u003cbr\u003eof cells, same\u003cbr\u003ecan be done\u003cbr\u003ewith prior\u003cbr\u003enotification*)\u003c\/td\u003e\n\u003ctd style=\"width: 89pt;\" width=\"118\" class=\"xl67\"\u003e-Cell Clamps:7,\u003cbr\u003eAdequate Silicon\u003cbr\u003eTubing for\u003cbr\u003eInterconnection.\u003cbr\u003e-Lid for cell\u003cbr\u003esampling arm: 7\u003cbr\u003e-Stirring bars: 7\u003cbr\u003e-Silicon rings:7\u003cbr\u003e-Dosage\u003cbr\u003ecompartment:7\u003cbr\u003e-Support disc:7\u003cbr\u003e-Alignment ring:7\u003cbr\u003e-Luer lock\u003cbr\u003econnectors for\u003cbr\u003ecell\u003cbr\u003eInterconnections:\u003cbr\u003e7 pairs\u003cbr\u003e-IQ, OQ\u003cbr\u003edocuments\u003cbr\u003e-Ethernet cable\u003cbr\u003e-Software DVD,\u003cbr\u003eInlab calibration\u003cbr\u003ecertificate for\u003cbr\u003eDiffusion cell and\u003cbr\u003eequipment\u003c\/td\u003e\n\u003ctd style=\"width: 69pt;\" width=\"91\" class=\"xl67\"\u003e-Diffusion\u003cbr\u003ecell of 5ml,\u003cbr\u003e7ml, 12ml\u003cbr\u003e-Precise\u003cbr\u003esample\u003cbr\u003ewithdrawal\u003cbr\u003eglass\u003cbr\u003esyringe\u003cbr\u003e-NABL\u003cbr\u003eaccredited\u003cbr\u003elab\u003cbr\u003ecalibration\u003cbr\u003ecertificate\u003cbr\u003efor diffusion\u003cbr\u003ecell\u003cbr\u003e-PVT\u003cbr\u003edocumentati\u003cbr\u003eon\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 350.0pt;\" height=\"467\"\u003e\n\u003ctd style=\"height: 350.0pt; width: 48pt;\" width=\"64\" class=\"xl67\" height=\"467\"\u003eJFDC 07-\u003cbr\u003eO30 x 2\u003cbr\u003e(Dual\u003cbr\u003estirrer\u003cbr\u003eunit)\u003c\/td\u003e\n\u003ctd style=\"width: 83pt;\" width=\"110\" class=\"xl67\"\u003e6 stage\u003cbr\u003eelectromagnetic\u003cbr\u003estirrer drive: 02\u003c\/td\u003e\n\u003ctd style=\"width: 70pt;\" width=\"93\" class=\"xl67\"\u003eDouble wall\u003cbr\u003eHeated\u003cbr\u003ecirculating\u003cbr\u003ewater bath:\u003cbr\u003e01 unit\u003c\/td\u003e\n\u003ctd style=\"width: 75pt;\" width=\"100\" class=\"xl67\"\u003eGlass diffusion\u003cbr\u003ecell of 20ml\u003cbr\u003ecapacity with\u003cbr\u003e20mm\u003cbr\u003eexposure area:\u003cbr\u003e12 Nos\u003cbr\u003e(20ml cells are\u003cbr\u003eby default. If\u003cbr\u003euser wants to\u003cbr\u003eselect any\u003cbr\u003eother capacity\u003cbr\u003eof cells, same\u003cbr\u003ecan be done\u003cbr\u003ewith prior\u003cbr\u003enotification*)\u003c\/td\u003e\n\u003ctd style=\"width: 89pt;\" width=\"118\" class=\"xl67\"\u003e-Cell Clamps:14\u003cbr\u003eAdequate Silicon\u003cbr\u003eTubing for\u003cbr\u003eInterconnections\u003cbr\u003e-Lid for cell\u003cbr\u003esampling arm: 14\u003cbr\u003e-Stirring bars: 14\u003cbr\u003e-Silicon rings:14\u003cbr\u003e-Dosage\u003cbr\u003ecompartment:14\u003cbr\u003e-Support disc:14\u003cbr\u003e-Alignment ring:14\u003cbr\u003e-Luer lock\u003cbr\u003econnectors for\u003cbr\u003ecell\u003cspan style=\"mso-spacerun: yes;\"\u003e     \u003c\/span\u003eInterconnections:\u003cbr\u003e14pairs\u003cbr\u003e-IQ, OQ\u003cbr\u003edocuments\u003cbr\u003e-Ethernet cable\u003cbr\u003e-Software DVD,\u003cbr\u003eInlab calibration\u003cbr\u003ecertificate for\u003cbr\u003eDiffusion cell and\u003cbr\u003eequipment\u003c\/td\u003e\n\u003ctd class=\"xl68\"\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003ePerformance Verification Test (PVT) for Diffusion Cell Apparatus:\u003c\/strong\u003e\u003c\/em\u003e\u003cbr\u003e\u003cem\u003e\u003cstrong\u003e(Suitable for Model JFDC 07-O30)\u003c\/strong\u003e\u003c\/em\u003e\u003cbr\u003eThe Vertical Diffusion Cell (VDC) is an in vitro laboratory device for the study of drug release and permeation of semi-solid topical formulations and topical patches. Franz Diffusion Cell is a type of VDC. It is the industry standard for IVRT as well as IVPT studies. However, this Franz diffusion cell needs to pass physical acceptance criteria and performance verification test before performing IVRT\/IVPT studies.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cem\u003e\u003cstrong\u003eBenefits of Performance Verification Test (PVT) a USP requirement:\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGlobally recognized method for Metrology aspects: PVT covers both mechanical and analytical parts of franz diffusion cell apparatus.\u003c\/li\u003e\n\u003cli\u003eAbility to uncover the influence of unforeseen system variables in franz diffusion cell apparatus.\u003c\/li\u003e\n\u003cli\u003eAbility to compare intra\/inter lab variation: PVT is a holistic test and involves system suitability testing by reference standard material (USP 1% Hydrocortisone cream), a validated reference standard cream with pre-established testing characteristics.\u003c\/li\u003e\n\u003cli\u003eA necessity for IVRT\/IVPT studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003ePVT test will cover:\u003c\/strong\u003e\u003c\/em\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePhysical Acceptance Criteria according to USP General Chapter \u0026lt;725\u0026gt; and \u0026lt;1724\u0026gt; for parameters like the capacity of cells, the diameter of the orifice, the temperature of receptor medium, the temperature of the membrane surface, and magnetic stirrer speed.\u003c\/li\u003e\n\u003cli\u003ePerformance Verification Test of VDC Systems using the USP Hydrocortisone Cream for parameters like Cumulative amount of drug (Hydrocortisone) release per square cm and Confidence Interval using HPLC as an analytical method.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/JFDC_06-_O30_data.png?v=1783533661\" alt=\"\"\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Orchid Scientific","offers":[{"title":"Default Title","offer_id":41511698923578,"sku":"JFDC 07- O30","price":9072.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/JFDC06-O30HR_d1f16d7a-ade4-49b4-810e-cc87b3298ada.jpg?v=1783535877","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/orchid-scientific-diffusion-cell-apparatus-with-external-temperature-sensor","provider":"MSE Supplies","version":"1.0","type":"link"}