{"product_id":"nf-b-p105-p50-polyclonal-antibody","title":"NFκB-p105\/p50 Polyclonal Antibody","description":"\u003ch2\u003eNFκB-p105\/p50 Polyclonal Antibody\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable style=\"height: 71.7814px;\" width=\"503\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"height: 10px; width: 156.719px;\" width=\"137\"\u003eSKU #\u003c\/td\u003e\n\u003ctd style=\"height: 10px; width: 387.281px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-32226\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 19.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003eHuman, \u003cspan\u003eMouse\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 22.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 22.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 22.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 156.719px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003eWB, IHC-p, \u003cspan\u003eIF\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 99.8214%; height: 554.625px;\" class=\"pro-table\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eHuman, Mouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eWB, IHC-p, IF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eSynthesized peptide derived from human NFκB-p105\/p50 around the non-phosphorylation site of Ser337.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eNFκB-p105\/p50\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 117.562px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eDKFZp686C01211,  DNA binding factor KBF1,  DNA binding factor KBF1 EBP1,  DNA-binding factor KBF1,  EBP 1,  EBP-1,  EBP1,  KBF1,  MGC54151,  NF kB1,  NF kappa B,  NF kappaB,  NF kappabeta,  NFKB 1,  NFKB p105,  NFKB p50,  NFKB1,  NFkappaB,  Nfkb1,  Nuclear factor kappa B DNA binding subu,  nf b\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"P19838\" href=\"https:\/\/www.uniprot.org\/uniprot\/P19838\" target=\"_blank\"\u003eP19838\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003e105 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eObserved MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003e50 ,110kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eNucleus. Cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003e1 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eCancer,  Cell Biology,  Epigenetics and Nuclear Signaling,  Immunology,  Signal Transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%;\"\u003eThe product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 62.3438px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 21.375px;\"\u003e\n\u003ctd style=\"width: 35.3791%; height: 21.375px;\" class=\"bold\" width=\"30%\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 64.2599%; height: 21.375px;\" class=\"bold\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.375px;\"\u003e\n\u003ctd style=\"width: 35.3791%; height: 21.375px;\"\u003eWB\u003c\/td\u003e\n\u003ctd style=\"width: 64.2599%; height: 21.375px;\"\u003e1:500-1:2000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 35.3791%; height: 19.5938px;\"\u003eIHC\u003c\/td\u003e\n\u003ctd style=\"width: 64.2599%; height: 19.5938px;\"\u003e1:100-1:300\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 35.3791%;\"\u003eIF \u003c\/td\u003e\n\u003ctd style=\"width: 64.2599%;\"\u003e1:200-1:1000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNFkB is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. Activated NFkB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFkB has been associated with a number of inflammatory diseases while persistent inhibition of NFkB leads to inappropriate immune cell development or delayed cell growth. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. This antibody can bind both p105 and p50 isoforms of NFKB1.\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40876779143226,"sku":"E-AB-32226-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40876779175994,"sku":"E-AB-32226-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40876779208762,"sku":"E-AB-32226-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40876779241530,"sku":"E-AB-32226-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elabscience_4929fa81-1175-4947-bf23-81e02711d0be.jpg?v=1747831145","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/nf-b-p105-p50-polyclonal-antibody","provider":"MSE Supplies","version":"1.0","type":"link"}