{"product_id":"mcu-polyclonal-antibody","title":"MCU Polyclonal Antibody","description":"\u003ch2\u003eMCU Polyclonal Antibody\u003cbr\u003e\n\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 68.7775px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd width=\"137\" style=\"height: 10px; width: 214.5px;\"\u003eSKU #\u003c\/td\u003e\n\u003ctd height=\"38\" class=\"xl65\" width=\"102\" style=\"height: 10px; width: 329.5px;\"\u003eE-AB-93334\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 214.5px; height: 19.5925px;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 329.5px; height: 19.5925px;\"\u003e\u003cspan\u003eHuman\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd style=\"width: 214.5px; height: 19.5925px;\" width=\"170\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 329.5px; height: 19.5925px;\"\u003e\u003cspan\u003eRabbit\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd style=\"width: 214.5px; height: 19.5925px;\"\u003e\u003cspan\u003eApplications\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 329.5px; height: 19.5925px;\"\u003e\u003cspan\u003eWB\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 493.689px;\" class=\"dtl_table2\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 19.5925px;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 19.5925px;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 19.5925px;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 19.5925px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 19.5925px;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 19.5925px;\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 19.5925px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 19.5925px;\"\u003eWB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 19.5925px;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 19.5925px;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 23.7898px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 23.7898px;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 23.7898px;\"\u003eRecombinant fusion protein of human MCU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 19.5925px;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 19.5925px;\"\u003eMCU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1851px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 39.1851px;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 39.1851px;\"\u003eC10orf42, CCDC109A,  HsMCU,  mitochondrial calcium uniporter, MCU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 19.5925px;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 19.5925px;\"\u003e\n\u003cdiv\u003eQ8NE86\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 27.2212px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 27.2212px;\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 27.2212px;\"\u003e35 kDa\/36 kDa\/39 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1851px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 39.1851px;\"\u003eObserved MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 39.1851px;\"\u003eRefer to figures\n\u003cdiv class=\"position-relative\"\u003e\n\u003ci aria-hidden=\"true\" class=\"iconfont icon-question-circle fs_16\"\u003e\u003c\/i\u003eThe actual band is not consistent with the expectation.\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 31.2347px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 31.2347px;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 31.2347px;\"\u003eMitochondrial inner membrane, mitochondrion.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 19.5925px;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 19.5925px;\"\u003e1 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1851px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 39.1851px;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 39.1851px;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 19.5925px;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 19.5925px;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 19.5925px;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 19.5925px;\"\u003eCardiovascular, Metabolism\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5925px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 19.5925px;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 19.5925px;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1851px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 39.1851px;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 39.1851px;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1851px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4079%; height: 39.1851px;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%; height: 39.1851px;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 79.5314px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"30%\" class=\"bold\" style=\"width: 27.0758%; height: 19.5938px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd class=\"bold\" style=\"width: 72.5632%; height: 19.5938px;\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 27.0758%; height: 19.5938px;\"\u003e\u003cspan\u003eWB\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 72.5632%; height: 19.5938px;\"\u003e\u003cspan\u003e1:500-1:2000\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40872140734522,"sku":"E-AB-93334-200","price":677.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40872140767290,"sku":"E-AB-93334-120","price":488.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40872140800058,"sku":"E-AB-93334-60","price":380.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/E-AB-93334.jpg?v=1747258335","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/mcu-polyclonal-antibody","provider":"MSE Supplies","version":"1.0","type":"link"}