{"product_id":"gnas-polyclonal-antibody-store-at-20-c","title":"GNAS Polyclonal Antibody Store at -20°C","description":"\u003ch2\u003eGNAS Polyclonal Antibody Store at -20°C\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable style=\"height: 78.3752px;\" width=\"503\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 196.188px;\" width=\"137\"\u003eSKU #\u003c\/td\u003e\n\u003ctd height=\"38\" class=\"xl65\" width=\"102\" style=\"height: 19.5938px; width: 339.812px;\"\u003eE-AB-14088\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 196.188px; height: 19.5938px;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 339.812px; height: 19.5938px;\"\u003e\u003cspan\u003eHuman,  Mouse,  Rat\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 196.188px; height: 19.5938px;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 339.812px; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 196.188px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 339.812px; height: 19.5938px;\"\u003e\u003cspan\u003eWB,  IHC\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 99.8182%; height: 406.094px;\" class=\"pro-table\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eHuman,  Mouse,  Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eWB,  IHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eRecombinant protein of human GNAS\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eGNAS\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 24.219px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eAHO,  C20orf45,  GNAS1,  GPSA,  GSA,  GSP,  NESP,  PHP1A,  PHP1B,  PHP1C,  POH\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003e\n\u003cdiv\u003e\u003ca href=\"https:\/\/www.uniprot.org\/uniprot\/P63092\" title=\"P63092\" class=\"text-primary mr-2\" target=\"_blank\"\u003eP63092\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003e46 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eCytosol, Extracellular region or secreted, extracellular exosome, Golgi apparatus, trans-Golgi network membrane, Plasma Membrane, heterotrimeric G-protein complex, plasma membrane, Other locations: cytoplasm, intrinsic component of membrane, membrane.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.8542px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003e0.4 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 32.5208px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eCancer,  Metabolism,  Signal Transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 15.0561%;\" width=\"170\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 84.7112%;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 67.1459px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 25.3125px;\"\u003e\n\u003ctd style=\"width: 31.0549%; height: 25.3125px;\" class=\"bold\" width=\"30%\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 68.6391%; height: 25.3125px;\" class=\"bold\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 31.0549%;\"\u003e\u003cspan\u003eWB\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 68.6391%;\"\u003e\u003cspan\u003e1:200-1:1000\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 31.0549%;\"\u003e\u003cspan\u003eIHC\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 68.6391%;\"\u003e\u003cspan\u003e1:25-1:100\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40851158335546,"sku":"E-AB-14088-200","price":339.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40851158368314,"sku":"E-AB-14088-120","price":204.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40851158401082,"sku":"E-AB-14088-60","price":121.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/PolyclonalAntibody_2622ee65-2e62-467e-b0e4-90a8b64d3806.jpg?v=1744985465","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/gnas-polyclonal-antibody-store-at-20-c","provider":"MSE Supplies","version":"1.0","type":"link"}