{"product_id":"fndc3b-polyclonal-antibody","title":"FNDC3B Polyclonal Antibody","description":"\u003ch2\u003eFNDC3B Polyclonal Antibody\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 71.7814px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 10px;\"\u003e\u003cspan\u003eSKU #\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"height: 10px; width: 363.281px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-52260\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 20.5938px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 20.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px; height: 20.5938px;\"\u003eHuman, \u003cspan\u003eMouse\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.5938px;\"\u003e\n\u003ctd style=\"width: 180.719px; height: 21.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px; height: 21.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 180.719px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 363.281px;\"\u003eIHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 130%; height: 466.251px;\" class=\"pro-table\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eHuman, Mouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eIHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eFull length fusion protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eFNDC3B\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 93.9688px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eDKFZp686D14170 ,  DKFZp762K137,  FAD104,  FLJ23399,  Factor for adipocyte differentiation 104,  HCV NS5A binding protein 37 ,  MGC10002,  NS5ABP37,  PRO4979,  YVTM2421,  fibronectin type III domain containing 3B\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"Q53EP0\" href=\"https:\/\/www.uniprot.org\/uniprot\/Q53EP0\" target=\"_blank\"\u003eQ53EP0\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eMembrane, Single pass membrane protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003e1.8 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eAntigen affinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eMetabolism,  Signal transduction,  Stem cells\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.0997%;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 75.6233%;\"\u003eThe product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 42.75px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 21.375px;\"\u003e\n\u003ctd width=\"30%\" class=\"bold\" style=\"width: 39.6267%; height: 21.375px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd class=\"bold\" style=\"width: 60.0122%; height: 21.375px;\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.375px;\"\u003e\n\u003ctd style=\"width: 39.6267%; height: 21.375px;\"\u003eIHC\u003c\/td\u003e\n\u003ctd style=\"width: 60.0122%; height: 21.375px;\"\u003e1:30-1:150\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAdipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40893838786618,"sku":"E-AB-52260-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40893838819386,"sku":"E-AB-52260-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40893838852154,"sku":"E-AB-52260-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40893838884922,"sku":"E-AB-52260-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elabscience_288bc6f2-3c16-4bdb-9099-99388cbd536f.jpg?v=1748947596","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/fndc3b-polyclonal-antibody","provider":"MSE Supplies","version":"1.0","type":"link"}