{"product_id":"flna-polyclonal-antibody-reactivity-human","title":"FLNA Polyclonal Antibody Reactivity Human","description":"\u003ch2\u003eFLNA Polyclonal Antibody Reactivity Human\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 71.7814px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd width=\"137\" style=\"height: 10px; width: 156.719px;\"\u003eSKU #\u003c\/td\u003e\n\u003ctd style=\"height: 10px; width: 387.281px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-31433\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 19.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003eHuman, \u003cspan\u003eMouse, Rat\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 22.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 22.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 22.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 156.719px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003eWB, IHC-p\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pro-table\" style=\"width: 99.8214%; height: 547.625px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eHuman, Mouse, Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eWB, IHC-p\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 39.1875px;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 39.1875px;\"\u003eSynthesized peptide derived from human Filamin 1 around the non-phosphorylation site of Ser2152.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eFilamin 1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 117.562px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 117.562px;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 117.562px;\"\u003eABP 280,  ABP-280,  APBX,  Actin-binding protein 280,  Alpha filamin,  Alpha-filamin,  CSBS,  CVD1,  Endothelial actin binding protein,  Endothelial actin-binding protein,  FLN,  FLN-A,  FLN1,  FLNA,  FMD,  Filamin 1,  Filamin A,  Filamin A alpha,  Filamin-1,  Filamin-A,  MNS,  NHBP,  Non musc\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"P21333\" href=\"https:\/\/www.uniprot.org\/uniprot\/P21333\" target=\"_blank\"\u003eP21333\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003e281 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eObserved MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003e280 kDa\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eCytoplasm\u0026gt;cell cortex. Cytoplasm\u0026gt;cytoskeleton.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003e1 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 39.1875px;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 39.1875px;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eCancer,  Signal Transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 39.1875px;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 39.1875px;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 38.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 38.1875px;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 38.1875px;\"\u003eThe product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 58.7814px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"30%\" class=\"bold\" style=\"width: 35.3791%; height: 19.5938px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd class=\"bold\" style=\"width: 64.2599%; height: 19.5938px;\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 35.3791%; height: 19.5938px;\"\u003eWB\u003c\/td\u003e\n\u003ctd style=\"width: 64.2599%; height: 19.5938px;\"\u003e1:500-1:2000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 35.3791%; height: 19.5938px;\"\u003eIHC\u003c\/td\u003e\n\u003ctd style=\"width: 64.2599%; height: 19.5938px;\"\u003e1:100-1:300\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40876706365498,"sku":"E-AB-31433-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40876706398266,"sku":"E-AB-31433-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40876706431034,"sku":"E-AB-31433-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40876706463802,"sku":"E-AB-31433-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elabscience_5cf44383-c013-4041-93d9-0eedefe6f93f.jpg?v=1747809302","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/flna-polyclonal-antibody-reactivity-human","provider":"MSE Supplies","version":"1.0","type":"link"}