{"product_id":"fak-polyclonal-antibody-reactivity-human","title":"FAK Polyclonal Antibody Reactivity Human","description":"\u003ch2\u003eFAK Polyclonal Antibody Reactivity Human\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 81.3752px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"137\" style=\"height: 19.5938px; width: 156.719px;\"\u003eSKU #\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; width: 387.281px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-31400\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 19.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003eHuman, \u003cspan\u003eMouse, Rat\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 22.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 22.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 22.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 156.719px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003eWB, IHC-p\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pro-table\" style=\"width: 99.8214%; height: 568.219px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eHuman, Mouse, Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eWB, IHC-p\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 39.1875px;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 39.1875px;\"\u003eSynthesized peptide derived from human FAK around the non-phosphorylation site of Tyr407.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eFAK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 117.562px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 117.562px;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 117.562px;\"\u003eFADK,  FADK 1,  FAK related non kinase polypeptide,  FAK1,  FRNK,  Focal adhesion Kinase,  Focal adhesion kinase 1,  Focal adhesion kinase isoform FAK Del33,  Focal adhesion kinase related nonkinase,  PPP1R71,  Protein phosphatase 1 regulatory subunit 7,  p125FAK,  pp125FAK\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"Q05397\" href=\"https:\/\/www.uniprot.org\/uniprot\/Q05397\" target=\"_blank\"\u003eQ05397\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003e119 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eObserved MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003e119 kDa\n\u003cdiv class=\"position-relative\"\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 39.1875px;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 39.1875px;\"\u003eCell junction\u0026gt;focal adhesion. Cell membrane. Constituent of focal adhesions.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003e1 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 39.1875px;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 39.1875px;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eCancer, Cardiovascular,  Signal Transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 19.5938px;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 19.5938px;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 39.1875px;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 39.1875px;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4656%; height: 39.1875px;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 68.1755%; height: 39.1875px;\"\u003eThe product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 60.7814px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"30%\" class=\"bold\" style=\"width: 35.3791%; height: 19.5938px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd class=\"bold\" style=\"width: 64.2599%; height: 19.5938px;\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.5938px;\"\u003e\n\u003ctd style=\"width: 35.3791%; height: 21.5938px;\"\u003eWB\u003c\/td\u003e\n\u003ctd style=\"width: 64.2599%; height: 21.5938px;\"\u003e1:500-1:2000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 35.3791%; height: 19.5938px;\"\u003eIHC\u003c\/td\u003e\n\u003ctd style=\"width: 64.2599%; height: 19.5938px;\"\u003e1:100-1:300\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNon-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40876700172346,"sku":"E-AB-31400-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40876700205114,"sku":"E-AB-31400-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40876700237882,"sku":"E-AB-31400-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40876700270650,"sku":"E-AB-31400-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elabscience_e08edb5d-ca39-4a7f-a72d-e6c062f71b59.jpg?v=1747808893","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/fak-polyclonal-antibody-reactivity-human","provider":"MSE Supplies","version":"1.0","type":"link"}