{"product_id":"elab-fluor-488-11-dutp","title":"Elab Fluor® 488-11-dUTP","description":"\u003ch2\u003eElab Fluor® 488-11-dUTP\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIntroduction\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eElab Fluor® 488-11-dUTP is a modified triphosphate that can be linked to the 3 '-OH terminal of DNA by terminal transferase. This triphosphate is linked between fluorescein and the nitrogenous base by an 11-atom chain, which effectively prevents static quenching of fluorescence and improves the efficiency of nucleotide binding to the 3 '-OH terminal of DNA\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cb\u003eProduct Details\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cb\u003eProperties\u003c\/b\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 156.8px;\" width=\"100%\" data-mce-style=\"width: 100%; height: 156.8px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 32.5847%; height: 19.6px;\" data-mce-style=\"width: 32.5847%; height: 19.6px;\"\u003e\u003cspan\u003eApplication\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 67.1944%; height: 19.6px;\" data-mce-style=\"width: 67.1944%; height: 19.6px;\"\u003e\u003cspan\u003eDNA Fragmentation\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 32.5847%; height: 19.6px;\" data-mce-style=\"width: 32.5847%; height: 19.6px;\"\u003e\u003cspan\u003eDetection method\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 67.1944%; height: 19.6px;\" data-mce-style=\"width: 67.1944%; height: 19.6px;\"\u003eFluorometric Method\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 32.5847%; height: 19.6px;\" data-mce-style=\"width: 32.5847%; height: 19.6px;\"\u003e\u003cspan\u003eSample type\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 67.1944%; height: 19.6px;\" data-mce-style=\"width: 67.1944%; height: 19.6px;\"\u003e\u003cspan\u003eParaffin section, frozen section, cell slide\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 32.5847%; height: 19.6px;\" data-mce-style=\"width: 32.5847%; height: 19.6px;\"\u003e\u003cspan\u003eDetection instrument\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 67.1944%; height: 19.6px;\" data-mce-style=\"width: 67.1944%; height: 19.6px;\"\u003e\u003cspan\u003eFluorescence Microscope\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 32.5847%; height: 19.6px;\" data-mce-style=\"width: 32.5847%; height: 19.6px;\"\u003e\u003cspan\u003eDye Type\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 67.1944%; height: 22.6625px;\" data-mce-style=\"width: 67.1944%; height: 22.6625px;\"\u003e\n\u003cspan\u003eElab Fluor\u003c\/span\u003e\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e 488\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 32.5847%; height: 19.6px;\" data-mce-style=\"width: 32.5847%; height: 19.6px;\"\u003e\u003cspan\u003eEx\/Em (nm)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 67.1944%;\" data-mce-style=\"width: 67.1944%;\"\u003e495\/519\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 32.5847%; height: 19.6px;\" data-mce-style=\"width: 32.5847%; height: 19.6px;\"\u003e\u003cspan\u003eChannel set\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 67.1944%; height: 19.6px;\" data-mce-style=\"width: 67.1944%; height: 19.6px;\"\u003eFITC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 32.5847%; height: 19.6px;\" data-mce-style=\"width: 32.5847%; height: 19.6px;\"\u003e\u003cspan\u003eFilter set\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 67.1944%; height: 19.6px;\" data-mce-style=\"width: 67.1944%; height: 19.6px;\"\u003e\u003cspan\u003eFITC\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 32.5847%; height: 19.6px;\" data-mce-style=\"width: 32.5847%; height: 19.6px;\"\u003e\u003cspan\u003eStorage\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 67.1944%; height: 19.6px;\" data-mce-style=\"width: 67.1944%; height: 19.6px;\"\u003e\u003cspan\u003e-20°C, shading light\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 32.5847%; height: 19.6px;\" data-mce-style=\"width: 32.5847%; height: 19.6px;\"\u003e\u003cspan\u003eShipping\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 67.1944%; height: 19.6px;\" data-mce-style=\"width: 67.1944%; height: 19.6px;\"\u003eIce bag\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"width: 32.5847%; height: 19.6px;\" data-mce-style=\"width: 32.5847%; height: 19.6px;\"\u003e\u003cspan\u003eExpiration date\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 67.1944%; height: 19.6px;\" data-mce-style=\"width: 67.1944%; height: 19.6px;\"\u003e\u003cspan\u003e24 months\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb style=\"font-size: 0.875rem;\" data-mce-style=\"font-size: 0.875rem;\"\u003eDetection Principle\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eChromosome DNA breakage is an important marker event in cell apoptosis. A series of DNA 3'-OH terminus is produced by DNA double-strand breaks in apoptotic cells or whenever there is a gap in one strand. The fluorescein labeled dUTP can be linked to the 3' -OH terminus of the broken DNA under the action of terminal deoxyribonucleotide transferase (TdT). Fluorescence of dUTP conjugate can be detected by flow cytometer or fluorescence microscope.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 0.875rem;\" data-mce-style=\"font-size: 0.875rem;\"\u003eDetection\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elab_Fluor_488-11-dUTP.jpg?v=1714031519\" width=\"355\" height=\"266\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003eStore in the dark at -20°C for 12 months. Avoid repeated freezing and thawing. It is not recommended to vortex.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNotes\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eThis kit is for research use only.\u003c\/li\u003e\n\u003cli\u003eFor your safety and health, please wear the lab coat and disposable gloves before the experiments.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"250μL","offer_id":40439610703930,"sku":"E-CK-A121D-250","price":457.95,"currency_code":"USD","in_stock":true},{"title":"25μL","offer_id":40439610736698,"sku":"E-CK-A121D-25","price":156.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/E-CK-A121D.jpg?v=1714031800","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/elab-fluor-488-11-dutp","provider":"MSE Supplies","version":"1.0","type":"link"}