{"product_id":"crystallin-alpha-c-monoclonal-antibody","title":"Crystallin-Alpha C Monoclonal Antibody","description":"\u003ch2\u003eCrystallin-Alpha C Monoclonal Antibody\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable style=\"height: 75.7814px;\" width=\"503\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"height: 17px; width: 156.719px;\" width=\"137\"\u003eSKU #\u003c\/td\u003e\n\u003ctd style=\"height: 17px; width: 387.281px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-22177\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 19.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003e\u003cspan class=\"cat reg_tag\"\u003e\u003cspan\u003eHuman,  Mouse,  Rat\u003c\/span\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 19.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003e\u003cspan\u003eMouse\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 156.719px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003e\u003cspan\u003eWB\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 99.8182%; height: 641.781px;\" class=\"pro-table\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 19.5938px;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 19.5938px;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 19.5938px;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 19.5938px;\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 19.5938px;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 19.5938px;\"\u003eHuman,  Mouse,  Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 19.5938px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 19.5938px;\"\u003eWB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 19.5938px;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 19.5938px;\"\u003eMonoclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 19.5938px;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 19.5938px;\"\u003eRecombinant Protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 19.5938px;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 19.5938px;\"\u003eHSPB8\/HSP22\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 117.562px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 117.562px;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 117.562px;\"\u003eAlpha crystallin C chain,  Alpha-crystallin C chain,  CMT2L,  CRYAC,  Charcot Marie Tooth disease axonal type 2L,  Charcot Marie Tooth disease spinal,  DHMN 2,  DHMN2,  E2 induced gene 1 protein,  E2-induced gene 1 protein,  E2IG1,  H11,  Heat shock 22kDa protein 8,  Heat shock 27\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 19.5938px;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 19.5938px;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"Q9UJY1\" href=\"https:\/\/www.uniprot.org\/uniprot\/Q9UJY1\" target=\"_blank\"\u003eQ9UJY1\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 39.1875px;\"\u003eObserved MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 39.1875px;\"\u003e22 kDa\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 39.1875px;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 39.1875px;\"\u003eCytoplasm. Nucleus. Translocates to nuclear foci during heat shock.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 27.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 27.1875px;\"\u003eTissue Specificity\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 27.1875px;\"\u003ePredominantly expressed in skeletal muscle and heart\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 35.1875px;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 35.1875px;\"\u003e1 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 39.1875px;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 39.1875px;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 35.1875px;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 35.1875px;\"\u003eProtein A purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 19.5938px;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 19.5938px;\"\u003eCancer,  Neuroscience,  Signal Transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 23.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 23.1875px;\"\u003eClone No.\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 23.1875px;\"\u003e2C3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 31.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 31.1875px;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 31.1875px;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 39.1875px;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 39.1875px;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%; height: 39.1875px;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%; height: 39.1875px;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 58.7814px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 35.4596%; height: 19.5938px;\" class=\"bold\" width=\"30%\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 64.1793%; height: 19.5938px;\" class=\"bold\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 35.4596%;\"\u003eWB\u003c\/td\u003e\n\u003ctd style=\"width: 64.1793%;\"\u003e1:1000-2000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.\u003cbr\u003e\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40878482751546,"sku":"E-AB-22177-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40878482784314,"sku":"E-AB-22177-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40878482817082,"sku":"E-AB-22177-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40878482849850,"sku":"E-AB-22177-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/E-AB-22177-1.jpg?v=1747992740","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/crystallin-alpha-c-monoclonal-antibody","provider":"MSE Supplies","version":"1.0","type":"link"}