{"product_id":"cdk11a-b-polyclonal-antibody","title":"CDK11A\/B Polyclonal Antibody","description":"\u003ch2\u003eCDK11A\/B Polyclonal Antibody\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 74.7814px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 16px;\"\u003e\n\u003ctd width=\"137\" style=\"height: 16px; width: 197.297px;\"\u003eSKU #\u003c\/td\u003e\n\u003ctd height=\"38\" class=\"xl66\" width=\"102\" style=\"height: 16px; width: 346.703px;\"\u003eE-AB-16328\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 197.297px; height: 19.5938px;\" width=\"170\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 346.703px; height: 19.5938px;\"\u003e\u003cspan\u003eHuman\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 197.297px; height: 19.5938px;\" width=\"170\"\u003eHost\u003c\/td\u003e\n\u003ctd width=\"170\" style=\"width: 346.703px; height: 19.5938px;\"\u003e\u003cspan\u003eRabbit\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 197.297px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 346.703px; height: 19.5938px;\"\u003e\u003cspan\u003eIHC\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pro-table\" style=\"width: 134.126%; height: 382.469px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003eIHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003eSynthetic peptide of human CDK11A\/CDK11B\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003eCDK11A\/CDK11B\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.375px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 49.375px;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 49.375px;\"\u003eCDC2L1,  CDC2L2,  CDC2L3,  CDK11,  CDK11-p110,  CDK11-p110 \/ p58,  CDK11-p46,  CDK11-p58,  CLK-1,  PITSLRE,  PK58,  p58CDC2L1,  p58CLK-1,  p58GTA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003e\n\u003cdiv\u003e\n\u003ca class=\"text-primary mr-2\" title=\"Q9UQ88\" href=\"https:\/\/www.uniprot.org\/uniprot\/Q9UQ88\" target=\"_blank\"\u003eQ9UQ88\u003c\/a\u003e\u003ca class=\"text-primary mr-2\" title=\"P21127\" href=\"https:\/\/www.uniprot.org\/uniprot\/P21127\" target=\"_blank\"\u003eP21127\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003eNucleus, Other locations: cytoplasm.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003e0.6 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003eCancer, Epigenetics and Nuclear Signaling\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 19.5938px;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 19.5938px;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 23.3528%; height: 39.1875px;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 76.3662%; height: 39.1875px;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 48.4844px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 27.2969px;\"\u003e\n\u003ctd width=\"30%\" class=\"bold\" style=\"width: 31.0549%; height: 27.2969px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd class=\"bold\" style=\"width: 68.6391%; height: 27.2969px;\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.1875px;\"\u003e\n\u003ctd style=\"width: 31.0549%; height: 21.1875px;\"\u003e\u003cspan\u003eIHC\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 68.6391%; height: 21.1875px;\"\u003e\u003cspan\u003e1:50-1:200\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eCyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle.They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells.They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved.CDKs are relatively small proteins, witHuman, Mouseolecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain.By definition, a CDK binds a regulatory protein called a cyclin.Without cyclin, CDK has little kinase activity; only the cyclin-CDK complex is an active kinase.CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases.\u003c\/span\u003e\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40875696750650,"sku":"E-AB-16328-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40875696783418,"sku":"E-AB-16328-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40875696816186,"sku":"E-AB-16328-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40875696848954,"sku":"E-AB-16328-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/E-AB-16328.jpg?v=1747723034","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/cdk11a-b-polyclonal-antibody","provider":"MSE Supplies","version":"1.0","type":"link"}