{"product_id":"actn1-monoclonal-antibody","title":"ACTN1 Monoclonal Antibody","description":"\u003ch2\u003eACTN1 Monoclonal Antibody\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable style=\"height: 75.7814px;\" width=\"503\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 17px;\"\u003e\n\u003ctd style=\"height: 17px; width: 156.719px;\" width=\"137\"\u003eSKU #\u003c\/td\u003e\n\u003ctd style=\"height: 17px; width: 387.281px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-22127\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 19.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003e\u003cspan class=\"cat reg_tag\"\u003e\u003cspan\u003eHuman,  Mouse,  Rat\u003c\/span\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 19.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003e\u003cspan\u003eMouse\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 156.719px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003e\u003cspan\u003eIHC-p\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 99.8182%; height: 512.391px;\" class=\"pro-table\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eHuman,  Mouse,  Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eIHC-p\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eMonoclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eRecombinant Protein of a-actinin of ACTN1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eACTN1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 34.5469px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eACTN 1,  ACTN1,  Actinin alpha 1,  Actn1,  Alpha Actinin 1,  Alpha actinin cytoskeletal isoform,  Alpha-actinin cytoskeletal isoform,  Alpha-actinin-1,  BDPLT15,  F,  F actin cross linking protein,  F-actin cross-linking protein,  FLJ40884,  actinin,  actinin 1 smooth muscle,  alpha 1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"P12814\" href=\"https:\/\/www.uniprot.org\/uniprot\/P12814\" target=\"_blank\"\u003eP12814\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eCytoplasm\u0026gt;cytoskeleton. Cytoplasm\u0026gt;myofibril\u0026gt;sarcomere\u0026gt;Z line. Colocalizes with MYOZ2 and PPP3CA at the Z-line of heart and skeletal muscle.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003e1 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eProtein A purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eCancer,  Developmental Biology,  Signal Transduction,  Stem Cells\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eClone No.\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003e1D4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 24.5945%;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 75.0494%;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 58.7814px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 35.4596%; height: 19.5938px;\" class=\"bold\" width=\"30%\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 64.1793%; height: 19.5938px;\" class=\"bold\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 35.4596%;\"\u003eIHC\u003c\/td\u003e\n\u003ctd style=\"width: 64.1793%;\"\u003e1:100-200\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.\u003cbr\u003e\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40879518515258,"sku":"E-AB-22127-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40879518548026,"sku":"E-AB-22127-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40879518580794,"sku":"E-AB-22127-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40879518613562,"sku":"E-AB-22127-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/E-AB-22127-1.jpg?v=1748071824","url":"https:\/\/www.msesupplies.com\/en-gb\/products\/actn1-monoclonal-antibody","provider":"MSE Supplies","version":"1.0","type":"link"}