{"product_id":"xbp1-polyclonal-antibody-store-at-20-c-1","title":"XBP1 Polyclonal Antibody Store at -20°C","description":"\u003ch2\u003eXBP1 Polyclonal Antibody Store at -20°C\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable style=\"height: 78.3752px;\" width=\"503\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 196.188px;\" width=\"137\"\u003eSKU #\u003c\/td\u003e\n\u003ctd height=\"38\" class=\"xl65\" width=\"102\" style=\"height: 19.5938px; width: 339.812px;\"\u003eE-AB-14437\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 196.188px; height: 19.5938px;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 339.812px; height: 19.5938px;\"\u003e\u003cspan\u003eHuman\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 196.188px; height: 19.5938px;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 339.812px; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 196.188px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 339.812px; height: 19.5938px;\"\u003e\u003cspan\u003eIHC\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 99.8182%; height: 474.125px;\" class=\"pro-table\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eIHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eRecombinant protein of human XBP1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eXBP1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 46.812px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eTREB5,  Tax responsive element binding protein 5,  Tax-responsive element-binding protein 5,  X box binding protein 1,  X box binding protein 2,  X-box-binding protein 1,  XBP 1,  XBP-1,  XBP1,  XBP2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"P17861\" href=\"https:\/\/www.uniprot.org\/uniprot\/P17861\" target=\"_blank\"\u003eP17861\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eNucleus.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003e0.2 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 32.5208px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eCancer,  Epigenetics and Nuclear Signaling\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 29.1771px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 32.5208px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 16.7382%;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 82.9552%;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 53.6042px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 28.4167px;\"\u003e\n\u003ctd style=\"width: 31.0549%; height: 28.4167px;\" class=\"bold\" width=\"30%\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 68.6391%; height: 28.4167px;\" class=\"bold\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 25.1875px;\"\u003e\n\u003ctd style=\"width: 31.0549%; height: 25.1875px;\"\u003e\u003cspan\u003eIHC\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 68.6391%; height: 25.1875px;\"\u003e\u003cspan\u003e1:50-1:200\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40853185790010,"sku":"E-AB-14437-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40853185822778,"sku":"E-AB-14437-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40853185855546,"sku":"E-AB-14437-60","price":328.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/PolyclonalAntibody_974cb23c-bc5b-4081-9146-d6494d0e2645.jpg?v=1745305318","url":"https:\/\/www.msesupplies.com\/en-de\/products\/xbp1-polyclonal-antibody-store-at-20-c-1","provider":"MSE Supplies","version":"1.0","type":"link"}