{"product_id":"tfeb-polyclonal-antibody","title":"TFEB Polyclonal Antibody","description":"\u003ch2\u003eTFEB Polyclonal Antibody\u003cbr\u003e\n\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable style=\"height: 96.7814px;\" width=\"503\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 38px;\"\u003e\n\u003ctd style=\"height: 38px; width: 214.5px;\" width=\"137\"\u003eSKU #\u003c\/td\u003e\n\u003ctd style=\"height: 38px; width: 329.5px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-93321\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 214.5px; height: 19.5938px;\" width=\"170\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 329.5px; height: 19.5938px;\"\u003e\u003cspan\u003eHuman, Mouse, Rat\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 214.5px; height: 19.5938px;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 329.5px; height: 19.5938px;\"\u003e\u003cspan\u003eRabbit\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 214.5px; height: 19.5938px;\"\u003e\u003cspan\u003eApplications\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 329.5px; height: 19.5938px;\"\u003e\u003cspan\u003eWB, IHC, IF\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"dtl_table2\" style=\"width: 100%; height: 540.782px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eHuman, Mouse, Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eWB, IHC, IF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 23.75px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eRecombinant fusion protein of human TFEB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eTFEB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eALPHATFEB, BHLHE35, TCFEB, TFEB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003e\n\u003cdiv\u003e\u003ca href=\"https:\/\/www.uniprot.org\/uniprot\/P34897\" title=\"P34897\" class=\"text-primary mr-2\" target=\"_blank\"\u003eP34897\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 27.1875px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003e53 kDa\/54 kDa\/55 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eObserved MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eRefer to figures\n\u003cdiv class=\"position-relative\"\u003e\u003ca role=\"button\" data-toggle=\"collapse\" href=\"https:\/\/www.elabscience.com\/p\/tfeb-polyclonal-antibody--e-ab-93321#collapseMW\" aria-expanded=\"true\" aria-controls=\"collapseMW\" class=\"text-secondary\" target=\"_blank\"\u003e\u003ci class=\"iconfont icon-question-circle fs_16\" aria-hidden=\"true\"\u003e\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003eThe actual band is not consistent with the expectation.\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 78.375px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eMitochondrion, Mitochondrion inner membrane, Mitochondrion matrix, mitochondrion nucleoid.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003e1 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eCancer,  Metabolism,  Signal Transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 31.4079%;\" width=\"170\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 68.231%;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 79.5314px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 27.0758%; height: 19.5938px;\" class=\"bold\" width=\"30%\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 72.5632%; height: 19.5938px;\" class=\"bold\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 27.0758%; height: 19.5938px;\"\u003e\u003cspan\u003eWB\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 72.5632%; height: 19.5938px;\"\u003e\u003cspan\u003e1:500-1:2000\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 27.0758%;\"\u003e\u003cspan\u003eIHC \u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 72.5632%;\"\u003e\u003cspan\u003e1:50-1:200\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 27.0758%;\"\u003e\u003cspan\u003eIF\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 72.5632%;\"\u003e\u003cspan\u003e1:50-1:200\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40874260627514,"sku":"E-AB-93321-200","price":677.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40874260660282,"sku":"E-AB-93321-120","price":488.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40874260693050,"sku":"E-AB-93321-60","price":380.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/E-AB-93321-1.jpg?v=1747780464","url":"https:\/\/www.msesupplies.com\/en-de\/products\/tfeb-polyclonal-antibody","provider":"MSE Supplies","version":"1.0","type":"link"}