{"product_id":"phospho-glucocorticoid-receptor-ser211-polyclonal-antibody","title":"Phospho-Glucocorticoid Receptor (Ser211) Polyclonal Antibody","description":"\u003ch2\u003ePhospho-Glucocorticoid Receptor (Ser211) Polyclonal Antibody\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 79.7814px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 21px;\"\u003e\n\u003ctd width=\"137\" style=\"height: 21px; width: 156.719px;\"\u003eSKU #\u003c\/td\u003e\n\u003ctd style=\"height: 21px; width: 387.281px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-21144\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 19.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003e\u003cspan\u003eHuman,  Mouse,  Rat\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 156.719px; height: 19.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003e\u003cspan\u003eRabbit\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 156.719px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 387.281px; height: 19.5938px;\"\u003e\u003cspan\u003eWB,  IHC-p\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pro-table\" style=\"width: 99.8182%; height: 512.391px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eHuman,  Mouse,  Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eWB,  IHC-p\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eSynthesized peptide derived from human GR around the phosphorylation site of Ser211\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eGCCR,  GCR,  GCRST,  GR,  GRL,  Glucocorticoid receptor,  Grl1,  Nuclear receptor subfamily 3 group C member 1,  glucocorticoid nuclear receptor variant 1,  group C,  member 1 (glucocorticoid receptor),  nr3c1,  nuclear receptor subfamily 3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 34.5469px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"P04150\" href=\"https:\/\/www.uniprot.org\/uniprot\/P04150\" target=\"_blank\"\u003eP04150\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003e86 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eObserved MW\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003e95 kDa\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eCytoplasm. Nucleus. Cytoplasmic in the absence of ligand, nuclear after ligand-binding and Nucleus. Localized largely in the nucleus.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eTissue Specificity\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eWidely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003e1 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eCancer,  Epigenetics and Nuclear Signaling,  Signal Transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 31.4665%;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 68.1775%;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 42.7188px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 23.125px;\"\u003e\n\u003ctd width=\"30%\" class=\"bold\" style=\"width: 35.4596%; height: 23.125px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd class=\"bold\" style=\"width: 64.1793%; height: 23.125px;\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 35.4596%;\"\u003eWB\u003c\/td\u003e\n\u003ctd style=\"width: 64.1793%;\"\u003e1:500-1:2000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 35.4596%; height: 19.5938px;\"\u003eIHC\u003c\/td\u003e\n\u003ctd style=\"width: 64.1793%; height: 19.5938px;\"\u003e1:100-1:300\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e   \u003c\/p\u003e\n\u003cp\u003eReceptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.\u003cbr\u003e\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40884364410938,"sku":"E-AB-21144-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40884364443706,"sku":"E-AB-21144-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40884364476474,"sku":"E-AB-21144-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40884364509242,"sku":"E-AB-21144-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/E-AB-21144-1.jpg?v=1748342449","url":"https:\/\/www.msesupplies.com\/en-de\/products\/phospho-glucocorticoid-receptor-ser211-polyclonal-antibody","provider":"MSE Supplies","version":"1.0","type":"link"}