{"product_id":"nf-b-p105-polyclonal-antibody-store-at-20-c","title":"NFκB-p105 Polyclonal Antibody Store at -20°C","description":"\u003ch2\u003eNFκB-p105 Polyclonal Antibody Store at -20°C\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable style=\"height: 78.3752px;\" width=\"503\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 196.188px;\" width=\"137\"\u003eSKU #\u003c\/td\u003e\n\u003ctd height=\"38\" class=\"xl65\" width=\"102\" style=\"height: 19.5938px; width: 339.812px;\"\u003eE-AB-13851\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 196.188px; height: 19.5938px;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 339.812px; height: 19.5938px;\"\u003e\u003cspan\u003eHuman\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 196.188px; height: 19.5938px;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 339.812px; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 196.188px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 339.812px; height: 19.5938px;\"\u003e\u003cspan\u003eIHC\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 99.8182%; height: 508.479px;\" class=\"pro-table\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 19.5938px;\" width=\"170\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 19.5938px;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 19.5938px;\" width=\"170\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 19.5938px;\" width=\"170\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 19.5938px;\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 19.5938px;\" width=\"170\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 19.5938px;\"\u003eIHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 19.5938px;\" width=\"170\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 19.5938px;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 19.5938px;\" width=\"170\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 19.5938px;\"\u003eRecombinant protein of human NFKB1p105\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 19.5938px;\" width=\"170\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 19.5938px;\"\u003eNFκB-p105\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 117.562px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 117.562px;\" width=\"170\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 117.562px;\"\u003eDKFZp686C01211,  DNA binding factor KBF1,  DNA binding factor KBF1 EBP1,  DNA-binding factor KBF1,  EBP 1,  EBP-1,  EBP1,  KBF1,  MGC54151,  NF kB1,  NF kappa B,  NF kappaB,  NF kappabeta,  NFKB 1,  NFKB p105,  NFKB p50,  NFKB1,  NFkappaB,  Nfkb1,  Nuclear factor kappa B DNA binding subu,  nf b\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 19.5938px;\" width=\"170\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 19.5938px;\"\u003e\n\u003cdiv\u003e\u003ca href=\"https:\/\/www.uniprot.org\/uniprot\/P19838\" title=\"P19838\" class=\"text-primary mr-2\" target=\"_blank\"\u003eP19838\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.6354px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 18.6354px;\" width=\"170\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 18.6354px;\"\u003eNucleus. Cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 19.5938px;\" width=\"170\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 19.5938px;\"\u003e0.3 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 39.1875px;\" width=\"170\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 39.1875px;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 19.5938px;\" width=\"170\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 19.5938px;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 39.1875px;\" width=\"170\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 39.1875px;\"\u003eCancer,  Cell Biology,  Epigenetics and Nuclear Signaling,  Immunology,  Signal Transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 19.5938px;\" width=\"170\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 19.5938px;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 39.1875px;\" width=\"170\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 39.1875px;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 31.821%; height: 39.1875px;\" width=\"170\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 67.6885%; height: 39.1875px;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 58.7814px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.0549%; height: 19.5938px;\" class=\"bold\" width=\"30%\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 68.6391%; height: 19.5938px;\" class=\"bold\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.0549%; height: 19.5938px;\"\u003e\u003cspan\u003eIHC\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 68.6391%; height: 19.5938px;\"\u003e\u003cspan\u003e1:25-1:100\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40849766973498,"sku":"E-AB-13851-200","price":339.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40849767006266,"sku":"E-AB-13851-120","price":204.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40849767039034,"sku":"E-AB-13851-60","price":121.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/PolyclonalAntibody_a6ceacf8-c83e-48eb-a24b-69f2e50051b2.jpg?v=1744821516","url":"https:\/\/www.msesupplies.com\/en-de\/products\/nf-b-p105-polyclonal-antibody-store-at-20-c","provider":"MSE Supplies","version":"1.0","type":"link"}