{"product_id":"mcm6-polyclonal-antibody-store-at-20-c","title":"MCM6 Polyclonal Antibody Store at -20°C","description":"\u003ch2\u003eMCM6 Polyclonal Antibody Store at -20°C\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable style=\"height: 76.7345px;\" width=\"503\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"height: 10px; width: 170.547px;\" width=\"137\"\u003eSKU #\u003c\/td\u003e\n\u003ctd style=\"height: 10px; width: 363.453px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-10451\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 170.547px; height: 19.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.453px; height: 19.5938px;\"\u003e\u003cspan\u003eHuman, Mouse, Rat\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 170.547px; height: 19.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.453px; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 27.5469px;\"\u003e\n\u003ctd style=\"height: 27.5469px; width: 170.547px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 363.453px; height: 27.5469px;\"\u003eWB, IHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"dtl_table2\" style=\"width: 100%; height: 558.266px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eHuman, Mouse, Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eWB, IHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eRecombinant protein of human MCM6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eMCM6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 137.156px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eDNA replication licensing factor MCM6,  MCG40308,  MCM6,  MCM6 minichromosome maintenance deficient 6,  MCM6 minichromosome maintenance deficient 6 (MIS5 homolog,  Mcm6,  Minichromosome maintenance complex component 6,  Minichromosome maintenance deficient (m,  S. pombe)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 36.1719px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"Q14566\" href=\"https:\/\/www.uniprot.org\/uniprot\/Q14566\" target=\"_blank\"\u003eQ14566\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003e93 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 36.25px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eNucleus. Binds to chromatin during G1 and detach from it during S phase.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003e0.6 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eCancer,  Epigenetics and Nuclear Signaling\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 31.9853%;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 62.3438px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 21.375px;\"\u003e\n\u003ctd style=\"width: 33.5381%; height: 21.375px;\" class=\"bold\" width=\"30%\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 66.0943%; height: 21.375px;\" class=\"bold\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.375px;\"\u003e\n\u003ctd style=\"width: 33.5381%; height: 21.375px;\"\u003eWB\u003c\/td\u003e\n\u003ctd style=\"width: 66.0943%; height: 21.375px;\"\u003e1:500-1:2000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 33.5381%; height: 19.5938px;\"\u003eIHC \u003c\/td\u003e\n\u003ctd style=\"width: 66.0943%; height: 19.5938px;\"\u003e1:50-1:200\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication.The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins.The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40847061516346,"sku":"E-AB-10451-200","price":339.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40847061549114,"sku":"E-AB-10451-120","price":204.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40847061581882,"sku":"E-AB-10451-60","price":121.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elabscience_b925fa9d-d65f-42a1-a264-bf676a99c531.jpg?v=1744437423","url":"https:\/\/www.msesupplies.com\/en-de\/products\/mcm6-polyclonal-antibody-store-at-20-c","provider":"MSE Supplies","version":"1.0","type":"link"}