{"product_id":"dsp-polyclonal-antibody-store-at-20-c","title":"DSP Polyclonal Antibody Store at -20°C","description":"\u003ch2\u003eDSP Polyclonal Antibody Store at -20°C\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable style=\"height: 68.7814px;\" width=\"503\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"height: 10px; width: 174.438px;\" width=\"137\"\u003eSKU #\u003c\/td\u003e\n\u003ctd style=\"height: 10px; width: 359.562px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-12373\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 174.438px; height: 19.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 359.562px; height: 19.5938px;\"\u003e\u003cspan\u003eHuman, Mouse\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 174.438px; height: 19.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 359.562px; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 174.438px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 359.562px; height: 19.5938px;\"\u003e\u003cspan\u003eIHC\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 99.8182%; height: 531.031px;\" class=\"pro-table\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eHuman, Mouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eIHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eSynthetic peptide of human DSP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eDSP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 117.562px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003e250\/210 kDa paraneoplastic pemphigus antigen,  DCWHKTA,  DESP,  DP,  DP I,  DP II,  DPI,  DPII,  DSP,  Desmoplakin,  Desmoplakin (DPI DPII),  Desmoplakin I,  Desmoplakin II,  KPPS2,  PPKS 2,  PPKS2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003e\n\u003cdiv\u003e\u003ca class=\"text-primary mr-2\" title=\"P15924\" href=\"https:\/\/www.uniprot.org\/uniprot\/P15924\" target=\"_blank\"\u003eP15924\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eCell junction, desmosome. Cytoplasm, cytoskeleton. Cell membrane. Innermost portion of the desmosomal plaque. Colocalizes with epidermal KRT5-KRT14 and simple KRT8-KRT18 keratins and VIM intermediate filaments network (PubMed:12802069). Localizes at the intercalated disk in cardiomyocytes (By similarity).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003e0.5 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eCancer,  Signal Transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 32.0442%;\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eThe product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 46.125px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 23.0625px;\"\u003e\n\u003ctd style=\"width: 31.0662%; height: 23.0625px;\" class=\"bold\" width=\"30%\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 68.5662%; height: 23.0625px;\" class=\"bold\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 31.0662%;\"\u003e\u003cspan\u003eIHC\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 68.5662%;\"\u003e\u003cspan\u003e1:50-1:200\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDesmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40858797637690,"sku":"E-AB-12373-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40858797670458,"sku":"E-AB-12373-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40858797703226,"sku":"E-AB-12373-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40858797735994,"sku":"E-AB-12373-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elabscience_d19125f7-47ae-474a-9fd0-ea6ae4e33cdc.jpg?v=1745841517","url":"https:\/\/www.msesupplies.com\/en-de\/products\/dsp-polyclonal-antibody-store-at-20-c","provider":"MSE Supplies","version":"1.0","type":"link"}