{"product_id":"ccdc99-polyclonal-antibody-store-at-20-c","title":"CCDC99 Polyclonal Antibody Store at -20°C","description":"\u003ch2\u003eCCDC99 Polyclonal Antibody Store at -20°C\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 29.5938px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"137\" style=\"height: 19.5938px; width: 171.188px;\"\u003eSKU #\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; width: 364.812px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-10614\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\" style=\"width: 171.188px;\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 364.812px;\"\u003e\u003cspan\u003eHuman,  Mouse\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 171.188px;\" width=\"170\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 364.812px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"height: 10px; width: 171.188px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 364.812px; height: 10px;\"\u003e\u003cspan\u003eWB\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pro-table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eIsotype\u003c\/td\u003e\n\u003ctd\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eHost\u003c\/td\u003e\n\u003ctd\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eReactivity\u003c\/td\u003e\n\u003ctd\u003eHuman,  Mouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eApplications\u003c\/td\u003e\n\u003ctd\u003eWB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eClonality\u003c\/td\u003e\n\u003ctd\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd\u003eRecombinant protein of human SPDL1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eAbbre\u003c\/td\u003e\n\u003ctd\u003eSPDL1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd\u003eAA409762,  Arsenite related gene 1 protein,  Arsenite-related gene 1 protein,  CCDC 99,  Ccdc99,  Coiled coil domain containing 99,  Coiled-coil domain-containing protein 99,  FLJ20364,  FLJ40690,  MGC124977,  Protein Spindly,  Rh,  hSpindly,  rhabdomyosarcoma antigen MU RMS 40.4A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd\u003e\n\u003cdiv\u003e\u003ca href=\"https:\/\/www.uniprot.org\/uniprot\/Q96EA4\" title=\"Q96EA4\" class=\"text-primary mr-2\" target=\"_blank\"\u003eQ96EA4\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd\u003e70\/59 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd\u003eCytoplasm\u0026gt;cytoskeleton\u0026gt;centrosome. Chromosome\u0026gt;centromere\u0026gt;kinetochore. Nucleus. Cytoplasm\u0026gt;cytoskeleton\u0026gt;spindle pole. Localizes to the nucleus in interphase and to the kinetochore in early prometaphase. Relocalizes to the mitotic spindle pole before metaphase and is subsequently lost from the spindle poles after chromosome congression is completed. Removal of this protein from the kinetochore requires the dynein\/dynactin complex.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eConcentration\u003c\/td\u003e\n\u003ctd\u003e0.2 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eBuffer\u003c\/td\u003e\n\u003ctd\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd\u003eCell Biology\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eConjugation\u003c\/td\u003e\n\u003ctd\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eStorage\u003c\/td\u003e\n\u003ctd\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"170\"\u003eShipping\u003c\/td\u003e\n\u003ctd\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 29.5938px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"30%\" class=\"bold\" style=\"width: 33.7803%; height: 19.5938px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd class=\"bold\" style=\"width: 65.9137%; height: 19.5938px;\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd style=\"width: 33.7803%; height: 10px;\"\u003e\u003cspan\u003eWB\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 65.9137%; height: 10px;\"\u003e\u003cspan\u003e1:500-1:2000\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRequired for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40847645802554,"sku":"E-AB-10614-200","price":339.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40847645835322,"sku":"E-AB-10614-120","price":204.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40847645868090,"sku":"E-AB-10614-60","price":121.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/PolyclonalAntibody_e9b6651e-a810-4165-9cb6-0734652e0b9b.jpg?v=1744531740","url":"https:\/\/www.msesupplies.com\/en-de\/products\/ccdc99-polyclonal-antibody-store-at-20-c","provider":"MSE Supplies","version":"1.0","type":"link"}