{"product_id":"appl1-polyclonal-antibody-store-at-20-c","title":"APPL1 Polyclonal Antibody Store at -20°C","description":"\u003ch2\u003eAPPL1 Polyclonal Antibody Store at -20°C\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 79.8908px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"137\" style=\"height: 19.5938px; width: 170.547px;\"\u003eSKU #\u003c\/td\u003e\n\u003ctd height=\"38\" class=\"xl65\" width=\"102\" style=\"height: 19.5938px; width: 363.453px;\"\u003eE-AB-10172\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 170.547px; height: 19.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.453px; height: 19.5938px;\"\u003eHuman, Mouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 170.547px; height: 19.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 363.453px; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.1094px;\"\u003e\n\u003ctd style=\"height: 21.1094px; width: 170.547px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 363.453px; height: 21.1094px;\"\u003eWB, IHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 476.766px;\" class=\"dtl_table2\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eHuman,  Mouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eWB,  IHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eRecombinant protein of human APPL1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eAPPL1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 38.547px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eAdapter protein containing PH domain,  Adaptor Protein Containing pH Domain,  Adaptor protein containing pH domain PTB domain and leucine zipper motif,  Adaptor protein containing pH domain PTB domain and leucine zipper motif 1,  Adaptor protein phosphotyrosine i\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003e\n\u003cdiv\u003e\u003ca href=\"https:\/\/www.uniprot.org\/uniprot\/Q9UKG1\" title=\"Q9UKG1\" class=\"text-primary mr-2\" target=\"_blank\"\u003eQ9UKG1\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003e80 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 42.75px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eEarly endosome membrane. Nucleus. Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 31.1875px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003e0.1 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eCancer,  Cell Biology,  Developmental Biology,  Neuroscience,  Signal Transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 31.1875px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 48.6094px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 27.4219px;\"\u003e\n\u003ctd width=\"30%\" class=\"bold\" style=\"width: 26.9325%; height: 27.4219px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd class=\"bold\" style=\"width: 72.6999%; height: 27.4219px;\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 21.1875px;\"\u003e\n\u003ctd style=\"width: 26.9325%; height: 21.1875px;\"\u003eWB\u003c\/td\u003e\n\u003ctd style=\"width: 72.6999%; height: 21.1875px;\"\u003e1:500-1:2000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 26.9325%;\"\u003eIHC\u003c\/td\u003e\n\u003ctd style=\"width: 72.6999%;\"\u003e1:100-1:300\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD\/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40844104400954,"sku":"E-AB-10172-200","price":339.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40844104433722,"sku":"E-AB-10172-120","price":204.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40844104466490,"sku":"E-AB-10172-60","price":121.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elabscience_bd8593fb-79f6-42b0-b9a0-7723d323df2a.jpg?v=1744192729","url":"https:\/\/www.msesupplies.com\/en-de\/products\/appl1-polyclonal-antibody-store-at-20-c","provider":"MSE Supplies","version":"1.0","type":"link"}