{"product_id":"abi1-polyclonal-antibody-store-at-20-c","title":"ABI1 Polyclonal Antibody Store at -20°C","description":"\u003ch2\u003eABI1 Polyclonal Antibody Store at -20°C\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 78.3752px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd width=\"137\" style=\"height: 19.5938px; width: 174.438px;\"\u003eSKU #\u003c\/td\u003e\n\u003ctd style=\"height: 19.5938px; width: 359.562px;\" width=\"102\" class=\"xl65\" height=\"38\"\u003eE-AB-12222\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 174.438px; height: 19.5938px;\"\u003e\u003cspan\u003eReactivity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 359.562px; height: 19.5938px;\"\u003e\u003cspan\u003eHuman, Mouse, Rat\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 174.438px; height: 19.5938px;\"\u003e\u003cspan\u003eHost\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 359.562px; height: 19.5938px;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"height: 19.5938px; width: 174.438px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 359.562px; height: 19.5938px;\"\u003e\u003cspan\u003eIHC\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable class=\"pro-table\" style=\"width: 99.8182%; height: 473.844px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eIsotype\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eHost\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eReactivity\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eHuman, Mouse, Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eWB, IHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eClonality\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eImmunogen\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eSynthetic peptide of human HTR1A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eAbbre\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eHTR1A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eSynonyms\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003e5 HT 1A,  5 HT receptor 1A,  5 HT1A,  5 HT1A receptor,  5 hydroxytryptamine (serotonin) receptor 1A,  5 hydroxytryptamine (serotonin) receptor 1A G protein coupled,  5 hydroxytryptamine receptor 1A,  5-HT-1A,  5-HT1A,  5-hydroxytryptamine receptor 1A,  5HT 1A,  5HT 1A receptor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eSwissprot\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003e\n\u003cdiv\u003e\u003ca href=\"https:\/\/www.uniprot.org\/uniprot\/P08908\" title=\"P08908\" class=\"text-primary mr-2\" target=\"_blank\"\u003eP08908\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eCalculated MW\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003e46 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eCellular Localization\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eCell membrane.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eConcentration\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003e0.6 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eBuffer\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003ePhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 31.1875px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003ePurification Method\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eAffinity purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 31.1875px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eResearch Areas\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eCancer,  Metabolism,  Neuroscience,  Signal Transduction\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eConjugation\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eStore at -20°C Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 32.0442%;\" width=\"170\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 67.5875%;\"\u003eThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRelated Reagents\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 34.7188px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 10px;\"\u003e\n\u003ctd width=\"30%\" class=\"bold\" style=\"width: 31.0662%; height: 10px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd class=\"bold\" style=\"width: 68.5662%; height: 10px;\"\u003eRecommended Dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 24.7188px;\"\u003e\n\u003ctd style=\"width: 31.0662%; height: 24.7188px;\"\u003e\u003cspan\u003eIHC\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 68.5662%; height: 24.7188px;\"\u003e\u003cspan\u003e1:50-1:200\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBackground\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"200μL","offer_id":40858202865722,"sku":"E-AB-12222-200","price":559.95,"currency_code":"USD","in_stock":true},{"title":"120μL","offer_id":40858202898490,"sku":"E-AB-12222-120","price":416.95,"currency_code":"USD","in_stock":true},{"title":"60μL","offer_id":40858202931258,"sku":"E-AB-12222-60","price":328.95,"currency_code":"USD","in_stock":true},{"title":"20μL","offer_id":40858202964026,"sku":"E-AB-12222-20","price":265.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/Elabscience_1d770f73-9c25-41b2-8da8-a263a09ad4dc.jpg?v=1745752432","url":"https:\/\/www.msesupplies.com\/en-de\/products\/abi1-polyclonal-antibody-store-at-20-c","provider":"MSE Supplies","version":"1.0","type":"link"}