{"product_id":"10-edta-decalcification-solution","title":"10% EDTA Decalcification Solution","description":"\u003ch2\u003e10% EDTA Decalcification Solution\u003cbr\u003e\n\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable width=\"503\" style=\"height: 61.7813px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 33.8438px;\"\u003e\n\u003ctd width=\"137\" style=\"height: 33.8438px; width: 182.547px;\"\u003eSKU #\u003c\/td\u003e\n\u003ctd height=\"38\" class=\"xl65\" width=\"102\" style=\"height: 28.5pt; width: 351.453px;\"\u003eE-IR-R112\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 27.9375px;\"\u003e\n\u003ctd width=\"170\" style=\"width: 182.547px;\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 351.453px;\"\u003eIHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 100%; height: 237px;\" class=\"dtl_table2\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 121.641px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eProduct Introduction\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eThere are many hard calcium tissue in pathological experiments. The density between calcium and paraffin in tissue are different, and tissue containing calcium can’t be sliced directly. Bone tissue contains the most calcium and calcification may occur in other tissues forming calcified areas in the tissue, it needs to decalcify. Decalcification is an important step in making bone slices, especially the bone tissue to immunohistochemical stained.\u003cbr\u003eEDTA can combine with calcium in the outer layer of hydroxyapatite crystal to form soluble non-ionic compounds, and promote the outward transfer of bound calcium in the inner layer of the crystal. With the continuity, the hydroxyapatite crystal is gradually melted, and it can play a chelating role when the pH is neutral. This method is characterized by long decalcification time, less damage to bone tissue, better preservation of enzyme activity (alkaline phosphatase) and cell antigenicity. The slices can be used for histochemical and immunohistochemical analysis.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 30.6875px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eApplications\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eIHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 23.6875px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eStore at room temperature Valid for 12 months. Avoid direct sunlight.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 60.9844px;\"\u003e\n\u003ctd style=\"width: 31.9853%;\" width=\"170\"\u003eShipping\u003c\/td\u003e\n\u003ctd style=\"width: 67.6471%;\"\u003eThe product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNotes\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. Sealed storage to prevent from pollution.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e2. This product couldn’t be used for clinical diagnosis or treatment, food or medicine, and can’t be stored in residence.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e3. For your safety and health, please wear the lab coat and disposable gloves before the experiments.\u003c\/span\u003e\u003c\/p\u003e","brand":"Elabscience Biotechnology","offers":[{"title":"1000mL","offer_id":40845484032058,"sku":"E-IR-R112-1000","price":299.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/7785\/files\/E-IR-R112.jpg?v=1744321145","url":"https:\/\/www.msesupplies.com\/en-de\/products\/10-edta-decalcification-solution","provider":"MSE Supplies","version":"1.0","type":"link"}